Expression of DNAL1 in cancer - Summary

CANCER ATLAS

Gene description

Dynein, axonemal, light chain 1

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Glioma

STAINING SUMMARY

HPA053129

GENE INFORMATION
Gene name	DNAL1 (HGNC Symbol)
Synonyms	1700010H15RiK, C14orf168, CILD16, MGC12435
Description	Dynein, axonemal, light chain 1 (HGNC Symbol)
Entrez gene summary	This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
Chromosome	14
Cytoband	q24.3
Chromosome location (bp)	73644875 - 73703732
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000119661 (version 83.38)
Entrez gene	83544
UniProt	Q4LDG9 (UniProt - Evidence at protein level)
neXtProt	NX_Q4LDG9
Antibodypedia	DNAL1 antibodies

PROTEIN BROWSER

DNAL1-001	DNAL1-002	DNAL1-004	DNAL1-005	DNAL1-006	DNAL1-009	DNAL1-010	DNAL1-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DNAL1-001 ENSP00000452037 ENST00000553645	Q4LDG9 [Direct mapping] Dynein light chain 1, axonemal Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	190 aa 21.5 kDa	No	0
DNAL1-002 ENSP00000310360 ENST00000311089	Q4LDG9 [Direct mapping] Dynein light chain 1, axonemal Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all		77 aa 8.9 kDa	No	0
DNAL1-004 ENSP00000452368 ENST00000554113	G3V5I4 [Direct mapping] Dynein light chain 1, axonemal Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		57 aa 6.7 kDa	No	0
DNAL1-005 ENSP00000451547 ENST00000555631	G3V424 [Direct mapping] Dynein light chain 1, axonemal Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	138 aa 15.7 kDa	No	0
DNAL1-006 ENSP00000451101 ENST00000555919	G3V389 [Direct mapping] Dynein light chain 1, axonemal Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	52 aa 5.6 kDa	No	0
DNAL1-009 ENSP00000450744 ENST00000554339	G3V2M0 [Direct mapping] Dynein light chain 1, axonemal Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		103 aa 11.9 kDa	No	0
DNAL1-010 ENSP00000451834 ENST00000554871	Q4LDG9 [Direct mapping] Dynein light chain 1, axonemal Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	151 aa 17.1 kDa	No	0
DNAL1-011 ENSP00000453439 ENST00000559993	H0YM28 [Direct mapping] Dynein light chain 1, axonemal Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		65 aa 7.6 kDa	No	0