Expression of ATL2 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Atlastin GTPase 2

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA029108

GENE INFORMATION
Gene name	ATL2 (HGNC Symbol)
Synonyms	ARL6IP2
Description	Atlastin GTPase 2 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband
Chromosome location (bp)	38294880 - 38377285
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000119787 (version 83.38)
Entrez gene	64225
UniProt	Q8NHH9 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NHH9
Antibodypedia	ATL2 antibodies

PROTEIN BROWSER

ATL2-001	ATL2-002	ATL2-004	ATL2-005	ATL2-007	ATL2-012	ATL2-013	ATL2-016	ATL2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATL2-001 ENSP00000415336 ENST00000419554	Q8NHH9 [Direct mapping] Atlastin-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0007029 [endoplasmic reticulum organization] GO:0007030 [Golgi organization] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0042802 [identical protein binding] GO:0051260 [protein homooligomerization] Show all	579 aa 66.1 kDa	No	2
ATL2-002 ENSP00000368237 ENST00000378954	Q8NHH9 [Direct mapping] Atlastin-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0007029 [endoplasmic reticulum organization] GO:0007030 [Golgi organization] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0042802 [identical protein binding] GO:0051260 [protein homooligomerization] Show all	583 aa 66.2 kDa	No	2
ATL2-004 ENSP00000390743 ENST00000452935	Q8NHH9 [Direct mapping] Atlastin-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0007029 [endoplasmic reticulum organization] GO:0007030 [Golgi organization] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0042802 [identical protein binding] GO:0051260 [protein homooligomerization] Show all	565 aa 64.5 kDa	No	2
ATL2-005 ENSP00000384062 ENST00000402054	Q8NHH9 [Direct mapping] Atlastin-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0007029 [endoplasmic reticulum organization] GO:0007030 [Golgi organization] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0042802 [identical protein binding] GO:0051260 [protein homooligomerization] Show all	412 aa 46.9 kDa	No	3
ATL2-007 ENSP00000404921 ENST00000451483	C9JC25 [Direct mapping] Atlastin-2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0008152 [metabolic process] Show all	186 aa 20.5 kDa	No	0
ATL2-012 ENSP00000409811 ENST00000449130	C9JQQ5 [Direct mapping] Atlastin-2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0008152 [metabolic process] Show all	175 aa 20.3 kDa	No	0
ATL2-013 ENSP00000385446 ENST00000406122	B5MCN0 [Direct mapping] Atlastin-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	413 aa 47.4 kDa	No	2
ATL2-016 ENSP00000410592 ENST00000443098	H7C3A2 [Direct mapping] Atlastin-2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0008152 [metabolic process] Show all	258 aa 30 kDa	No	0
ATL2-201 ENSP00000486809 ENST00000629272	B5MCN0 [Direct mapping] Atlastin-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	413 aa 47.4 kDa	No	2