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GNA13

GENERAL INFORMATION

Gene name

 GNA13

Gene description

 Guanine nucleotide binding protein (G protein), alpha 13

Protein class

 Cancer-related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA010087
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GNA13 (HGNC Symbol)

Synonyms

 G13, MGC46138

Description

 Guanine nucleotide binding protein (G protein), alpha 13 (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 q24.1

Chromosome location (bp)

 65010715 - 65056839

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000120063 (version 83.38)

Entrez gene

 10672

UniProt

 Q14344 (UniProt - Evidence at protein level)

neXtProt

 NX_Q14344

Antibodypedia

 GNA13 antibodies

PROTEIN BROWSER
GNA13-001
GNA13-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GNA13-001
ENSP00000400717
ENST00000439174
Q14344 [Direct mapping]
Guanine nucleotide-binding protein subunit alpha-13
A0A024R8M0 [Target identity:100%; Query identity:100%]
Guanine nucleotide binding protein (G protein), alpha 13, isoform CRA_a
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   Phobius predicted secreted proteins
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Mutated cancer genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001525 [angiogenesis]
GO:0001569 [patterning of blood vessels]
GO:0001664 [G-protein coupled receptor binding]
GO:0001701 [in utero embryonic development]
GO:0003924 [GTPase activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0005834 [heterotrimeric G-protein complex]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0006928 [movement of cell or subcellular component]
GO:0007165 [signal transduction]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway]
GO:0007204 [positive regulation of cytosolic calcium ion concentration]
GO:0007266 [Rho protein signal transduction]
GO:0007596 [blood coagulation]
GO:0008152 [metabolic process]
GO:0008360 [regulation of cell shape]
GO:0016020 [membrane]
GO:0019001 [guanyl nucleotide binding]
GO:0030154 [cell differentiation]
GO:0030168 [platelet activation]
GO:0030334 [regulation of cell migration]
GO:0031526 [brush border membrane]
GO:0031584 [activation of phospholipase D activity]
GO:0031683 [G-protein beta/gamma-subunit complex binding]
GO:0031702 [type 1 angiotensin receptor binding]
GO:0031752 [D5 dopamine receptor binding]
GO:0035556 [intracellular signal transduction]
GO:0042470 [melanosome]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 377 aa
44 kDa 		No 0
GNA13-002
ENSP00000439647
ENST00000541118
Q14344 [Direct mapping]
Guanine nucleotide-binding protein subunit alpha-13
Show all
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Mutated cancer genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005634 [nucleus]
GO:0005834 [heterotrimeric G-protein complex]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0006928 [movement of cell or subcellular component]
GO:0007165 [signal transduction]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007189 [adenylate cyclase-activating G-protein coupled receptor signaling pathway]
GO:0007266 [Rho protein signal transduction]
GO:0007596 [blood coagulation]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0019001 [guanyl nucleotide binding]
GO:0030168 [platelet activation]
GO:0031526 [brush border membrane]
GO:0031584 [activation of phospholipase D activity]
GO:0031683 [G-protein beta/gamma-subunit complex binding]
GO:0031702 [type 1 angiotensin receptor binding]
GO:0031752 [D5 dopamine receptor binding]
GO:0042470 [melanosome]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
Show all
 282 aa
33.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.