Cell atlas - RCL1 - The Human Protein Atlas

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RCL1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	RCL1
Gene description	RNA terminal phosphate cyclase-like 1
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Group enriched (HEL, HDLM-2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA071308
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (HEL, HDLM-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA071308	MCF7	Nucleoplasm
	HPA071308	SH-SY5Y	Nucleoplasm
	HPA071308	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	RCL1 (HGNC Symbol)
Synonyms	RNAC, RPCL1
Description	RNA terminal phosphate cyclase-like 1 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p24.1
Chromosome location (bp)	4792869 - 4885917
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000120158 (version 83.38)
Entrez gene	10171
UniProt	Q9Y2P8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2P8
Antibodypedia	RCL1 antibodies

PROTEIN BROWSER

RCL1-001	RCL1-002	RCL1-003	RCL1-004	RCL1-006	RCL1-007	RCL1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RCL1-001 ENSP00000371169 ENST00000381750	Q9Y2P8 [Direct mapping] RNA 3'-terminal phosphate cyclase-like protein Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000479 [endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0003723 [RNA binding] GO:0003824 [catalytic activity] GO:0004521 [endoribonuclease activity] GO:0005730 [nucleolus] GO:0006396 [RNA processing] GO:0008150 [biological_process] GO:0042254 [ribosome biogenesis] Show all	373 aa 40.8 kDa	No	0
RCL1-002 ENSP00000371149 ENST00000381730	Q9Y2P8 [Direct mapping] RNA 3'-terminal phosphate cyclase-like protein Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000479 [endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0003723 [RNA binding] GO:0003824 [catalytic activity] GO:0004521 [endoribonuclease activity] GO:0005730 [nucleolus] GO:0008150 [biological_process] GO:0042254 [ribosome biogenesis] Show all	187 aa 20.3 kDa	No	0
RCL1-003 ENSP00000412000 ENST00000442869	Q5VZU3 [Direct mapping] RNA 3'-terminal phosphate cyclase-like protein A0A087X1L9 [Target identity:100%; Query identity:100%] RNA 3'-terminal phosphate cyclase-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000479 [endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0003723 [RNA binding] GO:0003824 [catalytic activity] GO:0004521 [endoribonuclease activity] GO:0005730 [nucleolus] GO:0042254 [ribosome biogenesis] Show all	215 aa 23.3 kDa	No	0
RCL1-004 ENSP00000371151 ENST00000381732	Q5VYW8 [Direct mapping] RNA 3'-terminal phosphate cyclase-like protein Show all	MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000479 [endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0003723 [RNA binding] GO:0003824 [catalytic activity] GO:0004521 [endoribonuclease activity] GO:0005730 [nucleolus] Show all	175 aa 19.9 kDa	No	0
RCL1-006 ENSP00000371147 ENST00000381728	Q9Y2P8 [Direct mapping] RNA 3'-terminal phosphate cyclase-like protein Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000479 [endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0003723 [RNA binding] GO:0003824 [catalytic activity] GO:0004521 [endoribonuclease activity] GO:0005730 [nucleolus] GO:0008150 [biological_process] GO:0042254 [ribosome biogenesis] Show all	187 aa 20.3 kDa	No	0
RCL1-007 ENSP00000413381 ENST00000441844	Q5VZU2 [Direct mapping] RNA 3'-terminal phosphate cyclase-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000479 [endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0003723 [RNA binding] GO:0003824 [catalytic activity] GO:0004521 [endoribonuclease activity] GO:0005730 [nucleolus] Show all	138 aa 14.7 kDa	No	0
RCL1-201 ENSP00000388096 ENST00000448872	Q9Y2P8 [Direct mapping] RNA 3'-terminal phosphate cyclase-like protein Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000479 [endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0003723 [RNA binding] GO:0003824 [catalytic activity] GO:0004521 [endoribonuclease activity] GO:0005730 [nucleolus] GO:0008150 [biological_process] GO:0042254 [ribosome biogenesis] Show all	187 aa 20.3 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.