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SOHLH2

GENERAL INFORMATION

Gene name

 SOHLH2

Gene description

 Spermatogenesis and oogenesis specific basic helix-loop-helix 2

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Not detected
FANTOM5:Tissue enhanced (testis)

Protein evidence

 Evidence at transcript level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)

GENE INFORMATION

Gene name

 SOHLH2 (HGNC Symbol)

Synonyms

 bHLHe81, FLJ20449, SPATA28, TEB1

Description

 Spermatogenesis and oogenesis specific basic helix-loop-helix 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes one of testis-specific transcription factors which are essential for spermatogenesis, oogenesis and folliculogenesis. This gene is located on chromosome 13. The proteins encoded by this gene and another testis-specific transcription factor, SOHLH1, can form heterodimers, in addition to homodimers. There is a read-through locus (GeneID: 100526761) that shares sequence identity with this gene and the upstream CCDC169 (GeneID: 728591). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

Chromosome

 13

Cytoband

 q13.3

Chromosome location (bp)

 36168208 - 36214615

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000120669 (version 83.38)

Entrez gene

 54937

UniProt

 Q9NX45 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9NX45

Antibodypedia

 SOHLH2 antibodies

PROTEIN BROWSER
SOHLH2-001
SOHLH2-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SOHLH2-001
ENSP00000369210
ENST00000379881
Q9NX45 [Direct mapping]
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0046983 [protein dimerization activity]
GO:0048477 [oogenesis]
Show all
 425 aa
46.9 kDa 		No 0
SOHLH2-002
ENSP00000326838
ENST00000317764
Q9NX45 [Direct mapping]
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0046983 [protein dimerization activity]
GO:0048477 [oogenesis]
Show all
 225 aa
25.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.