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Several melanomas, urothelial, cervical, endometrial cancers along with few breast and skin cancers showed weak to moderate nuclear positivity. Other cancer tissues were generally negative.
Tumour cells generally showed weak to moderate cytoplasmic immunoreactivity. A few cases of prostate cancers showed strong staining. Renal cancers along with several cases of skin, testicular, urothelial and gastric cancers were negative.
GENE INFORMATION
Gene name
PROSER1 (HGNC Symbol)
Synonyms
bA50D16.2, C13orf23, FLJ12661
Description
Proline and serine rich 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a conserved protein containing proline and serine rich regions. These regions may be important in protein-protein interactions. [provided by RefSeq, Aug 2012]