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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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HSPH1
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

HSPH1

Gene description

Heat shock 105kDa/110kDa protein 1

Protein class

Cancer-related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Tissue enriched (vagina)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

Supported based on 2 antibodies.
HPA028675 , CAB002060
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Endometrium

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (vagina)

GENE INFORMATION

Gene name

HSPH1 (HGNC Symbol)

Synonyms

HSP105A, HSP105B, KIAA0201, NY-CO-25

Description

Heat shock 105kDa/110kDa protein 1 (HGNC Symbol)

Entrez gene summary

Chromosome

13

Cytoband

q12.3

Chromosome location (bp)

31134974 - 31162388

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000120694 (version 83.38)

Entrez gene

10808

UniProt

Q92598 (UniProt - Evidence at protein level)

neXtProt

NX_Q92598

Antibodypedia

HSPH1 antibodies

PROTEIN BROWSER

HSPH1-001
HSPH1-002
HSPH1-004
HSPH1-006
HSPH1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSPH1-001
ENSP00000318687
ENST00000320027
Q92598 [Direct mapping]
Heat shock protein 105 kDa
A0A024RDS1 [Target identity:100%; Query identity:100%]
Heat shock 105kDa/110kDa protein 1, isoform CRA_c
Show all
Predicted intracellular proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005576 [extracellular region]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006898 [receptor-mediated endocytosis]
GO:0006986 [response to unfolded protein]
GO:0034605 [cellular response to heat]
GO:0045345 [positive regulation of MHC class I biosynthetic process]
GO:0051135 [positive regulation of NK T cell activation]
GO:0070062 [extracellular exosome]
GO:0071682 [endocytic vesicle lumen]
GO:1900034 [regulation of cellular response to heat]
Show all
858 aa
96.9 kDa
No 0
HSPH1-002
ENSP00000369768
ENST00000380405
Q92598 [Direct mapping]
Heat shock protein 105 kDa
A0A024RDQ0 [Target identity:100%; Query identity:100%]
Heat shock 105kDa/110kDa protein 1, isoform CRA_a
Show all
Predicted intracellular proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005576 [extracellular region]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006898 [receptor-mediated endocytosis]
GO:0006986 [response to unfolded protein]
GO:0034605 [cellular response to heat]
GO:0045345 [positive regulation of MHC class I biosynthetic process]
GO:0051135 [positive regulation of NK T cell activation]
GO:0070062 [extracellular exosome]
GO:0071682 [endocytic vesicle lumen]
GO:1900034 [regulation of cellular response to heat]
Show all
814 aa
92.1 kDa
No 0
HSPH1-004
ENSP00000408991
ENST00000435381
Q5TBM3 [Direct mapping]
Heat shock protein 105 kDa
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
115 aa
13.2 kDa
No 0
HSPH1-006
ENSP00000487365
ENST00000630972
Q92598 [Direct mapping]
Heat shock protein 105 kDa
Show all
Predicted intracellular proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005874 [microtubule]
GO:0006898 [receptor-mediated endocytosis]
GO:0006986 [response to unfolded protein]
GO:0034605 [cellular response to heat]
GO:0043014 [alpha-tubulin binding]
GO:0045345 [positive regulation of MHC class I biosynthetic process]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0051085 [chaperone mediated protein folding requiring cofactor]
GO:0051135 [positive regulation of NK T cell activation]
GO:0061098 [positive regulation of protein tyrosine kinase activity]
GO:0070062 [extracellular exosome]
GO:0071682 [endocytic vesicle lumen]
GO:1900034 [regulation of cellular response to heat]
GO:1903748 [negative regulation of establishment of protein localization to mitochondrion]
GO:1903751 [negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide]
GO:1903753 [negative regulation of p38MAPK cascade]
GO:2001234 [negative regulation of apoptotic signaling pathway]
Show all
860 aa
97.5 kDa
No 0
HSPH1-201
ENSP00000396090
ENST00000445273
A0A0A0MSM0 [Direct mapping]
Heat shock protein 105 kDa
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
782 aa
88.8 kDa
No 0

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The Human Protein Atlas project is funded
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