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Several maligancies showed moderate to stong cytopslmic and/or nuclear staining.
Malignant lymphomas, carcinoid, liver and gastric cancers were negative.
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
P18146 [Direct mapping] Early growth response protein 1 Q546S1 [Target identity:100%; Query identity:100%] Early growth response 1, isoform CRA_a; Early growth response protein 1