Tissue expression of RDH10 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	RDH10
Gene description	Retinol dehydrogenase 10 (all-trans)
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	RDH10 (HGNC Symbol)
Synonyms	SDR16C4
Description	Retinol dehydrogenase 10 (all-trans) (HGNC Symbol)
Entrez gene summary	This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]
Chromosome	8
Cytoband	q21.11
Chromosome location (bp)	73294612 - 73325281
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000121039 (version 83.38)
Entrez gene	157506
UniProt	Q8IZV5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IZV5
Antibodypedia	RDH10 antibodies

PROTEIN BROWSER

RDH10-001	RDH10-002	RDH10-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RDH10-001 ENSP00000240285 ENST00000240285	Q8IZV5 [Direct mapping] Retinol dehydrogenase 10 A0A024R7X6 [Target identity:100%; Query identity:100%] Retinol dehydrogenase 10 (All-trans), isoform CRA_a Show all	Enzymes ENZYME proteins Oxidoreductases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001523 [retinoid metabolic process] GO:0001656 [metanephros development] GO:0001701 [in utero embryonic development] GO:0002138 [retinoic acid biosynthetic process] GO:0004745 [retinol dehydrogenase activity] GO:0005737 [cytoplasm] GO:0005789 [endoplasmic reticulum membrane] GO:0007601 [visual perception] GO:0007603 [phototransduction, visible light] GO:0008152 [metabolic process] GO:0008406 [gonad development] GO:0009887 [organ morphogenesis] GO:0014032 [neural crest cell development] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016491 [oxidoreductase activity] GO:0031076 [embryonic camera-type eye development] GO:0035115 [embryonic forelimb morphogenesis] GO:0042572 [retinol metabolic process] GO:0042574 [retinal metabolic process] GO:0043583 [ear development] GO:0043584 [nose development] GO:0044297 [cell body] GO:0048568 [embryonic organ development] GO:0048703 [embryonic viscerocranium morphogenesis] GO:0052650 [NADP-retinol dehydrogenase activity] GO:0055114 [oxidation-reduction process] GO:0060431 [primary lung bud formation] GO:0060449 [bud elongation involved in lung branching] Show all	341 aa 38.1 kDa	No	1
RDH10-002 ENSP00000428132 ENST00000519380	E5RK48 [Direct mapping] Retinol dehydrogenase 10 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	176 aa 19.8 kDa	No	0
RDH10-004 ENSP00000429727 ENST00000521928	E5RHJ9 [Direct mapping] Retinol dehydrogenase 10 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	62 aa 6.8 kDa	No	0