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A majority of cancer cells showed weak to moderate cytoplasmic positivity with additional membranous or nuclear positivity in many cases. A few cases of colorectal cancers were strongly stained. Many gliomas, skin, urothelial, gastric and renal cancers were weakly stained or negative.
A few cases of prostate, colorectal, breast and renal cancers displayed weak to moderate cytoplasmic positivity while nuclear and cytoplasmic staining was observed in ovarian cancer. Remaining cancer cells were generally negative.
GO:0002230 [positive regulation of defense response to virus by host] GO:0016021 [integral component of membrane] GO:0098779 [mitophagy in response to mitochondrial depolarization]