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Moderate cytoplasmic positivity was observed in most cancer tissues. Several cases of melanomas, endometrial and liver cancers showed strong cytoplasmic immunoreactivity.
GENE INFORMATION
Gene name
POLR3GL (HGNC Symbol)
Synonyms
flj32422, MGC3200
Description
Polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like (HGNC Symbol)
Q9BT43 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7-like
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Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000790 [nuclear chromatin] GO:0001056 [RNA polymerase III activity] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005666 [DNA-directed RNA polymerase III complex] GO:0005829 [cytosol] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006383 [transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter] GO:0006385 [transcription elongation from RNA polymerase III promoter] GO:0006386 [termination of RNA polymerase III transcription] GO:0010467 [gene expression] GO:0032481 [positive regulation of type I interferon production] GO:0045087 [innate immune response]
A6NGX6 [Direct mapping] DNA-directed RNA polymerase III subunit RPC7-like
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Predicted intracellular proteins RNA polymerase related proteins Protein evidence (Ezkurdia et al 2014)
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GO:0001056 [RNA polymerase III activity] GO:0006359 [regulation of transcription from RNA polymerase III promoter] GO:0006384 [transcription initiation from RNA polymerase III promoter]
