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ZRANB3

GENERAL INFORMATION

Gene name

 ZRANB3

Gene description

 Zinc finger, RAN-binding domain containing 3

Protein class

 Cancer-related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 ZRANB3 (HGNC Symbol)

Synonyms

 DKFZP434B1727

Description

 Zinc finger, RAN-binding domain containing 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q21.3

Chromosome location (bp)

 135136916 - 135531236

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000121988 (version 83.38)

Entrez gene

 84083

UniProt

 Q5FWF4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5FWF4

Antibodypedia

 ZRANB3 antibodies

PROTEIN BROWSER
ZRANB3-001
ZRANB3-002
ZRANB3-201
ZRANB3-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZRANB3-001
ENSP00000264159
ENST00000264159
Q5FWF4 [Direct mapping]
DNA annealing helicase and endonuclease ZRANB3 DNA annealing helicase ZRANB3 Endonuclease ZRANB3
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000733 [DNA strand renaturation]
GO:0003676 [nucleic acid binding]
GO:0004519 [endonuclease activity]
GO:0004520 [endodeoxyribonuclease activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0006281 [DNA repair]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0008270 [zinc ion binding]
GO:0009411 [response to UV]
GO:0031297 [replication fork processing]
GO:0036292 [DNA rewinding]
GO:0036310 [annealing helicase activity]
GO:0043596 [nuclear replication fork]
GO:0045910 [negative regulation of DNA recombination]
GO:0048478 [replication fork protection]
GO:0070530 [K63-linked polyubiquitin binding]
GO:0090305 [nucleic acid phosphodiester bond hydrolysis]
Show all
 1079 aa
123.2 kDa 		No 0
ZRANB3-002
ENSP00000383979
ENST00000401392
Q5FWF4 [Direct mapping]
DNA annealing helicase and endonuclease ZRANB3 DNA annealing helicase ZRANB3 Endonuclease ZRANB3
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000733 [DNA strand renaturation]
GO:0003676 [nucleic acid binding]
GO:0004519 [endonuclease activity]
GO:0004520 [endodeoxyribonuclease activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0006281 [DNA repair]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0008270 [zinc ion binding]
GO:0009411 [response to UV]
GO:0031297 [replication fork processing]
GO:0036292 [DNA rewinding]
GO:0036310 [annealing helicase activity]
GO:0043596 [nuclear replication fork]
GO:0045910 [negative regulation of DNA recombination]
GO:0048478 [replication fork protection]
GO:0070530 [K63-linked polyubiquitin binding]
GO:0090305 [nucleic acid phosphodiester bond hydrolysis]
Show all
 1077 aa
123.1 kDa 		No 0
ZRANB3-201
ENSP00000441320
ENST00000536680
F5GYN7 [Direct mapping]
DNA annealing helicase and endonuclease ZRANB3; Zinc finger, RAN-binding domain containing 3, isoform CRA_g
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Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0004519 [endonuclease activity]
GO:0008270 [zinc ion binding]
GO:0090305 [nucleic acid phosphodiester bond hydrolysis]
Show all
 625 aa
71.5 kDa 		No 0
ZRANB3-202
ENSP00000480120
ENST00000619650
Q5FWF4 [Direct mapping]
DNA annealing helicase and endonuclease ZRANB3 DNA annealing helicase ZRANB3 Endonuclease ZRANB3
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutated cancer genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000733 [DNA strand renaturation]
GO:0003676 [nucleic acid binding]
GO:0004519 [endonuclease activity]
GO:0004520 [endodeoxyribonuclease activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0006281 [DNA repair]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0008270 [zinc ion binding]
GO:0009411 [response to UV]
GO:0031297 [replication fork processing]
GO:0036292 [DNA rewinding]
GO:0036310 [annealing helicase activity]
GO:0043596 [nuclear replication fork]
GO:0045910 [negative regulation of DNA recombination]
GO:0048478 [replication fork protection]
GO:0070530 [K63-linked polyubiquitin binding]
GO:0090305 [nucleic acid phosphodiester bond hydrolysis]
Show all
 598 aa
67.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.