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ANXA11

GENERAL INFORMATION

Gene name

 ANXA11

Gene description

 Annexin A11

Protein class

 Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Transporters

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA027545 , CAB004851
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ANXA11 (HGNC Symbol)

Synonyms

 ANX11

Description

 Annexin A11 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, Dec 2015]

Chromosome

 10

Cytoband

 q22.3

Chromosome location (bp)

 80150889 - 80205572

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000122359 (version 83.38)

Entrez gene

 311

UniProt

 P50995 (UniProt - Evidence at protein level)

neXtProt

 NX_P50995

Antibodypedia

 ANXA11 antibodies

PROTEIN BROWSER
ANXA11-001
ANXA11-002
ANXA11-003
ANXA11-006
ANXA11-010
ANXA11-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ANXA11-001
ENSP00000361305
ENST00000372231
P50995 [Direct mapping]
Annexin A11
Q5T0G8 [Target identity:100%; Query identity:100%]
Annexin
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Transporters
   Primary Active Transporters
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0006909 [phagocytosis]
GO:0007049 [cell cycle]
GO:0016020 [membrane]
GO:0023026 [MHC class II protein complex binding]
GO:0030496 [midbody]
GO:0042470 [melanosome]
GO:0042581 [specific granule]
GO:0042582 [azurophil granule]
GO:0044548 [S100 protein binding]
GO:0044822 [poly(A) RNA binding]
GO:0045335 [phagocytic vesicle]
GO:0048306 [calcium-dependent protein binding]
GO:0051301 [cell division]
GO:0051592 [response to calcium ion]
GO:0070062 [extracellular exosome]
Show all
 505 aa
54.4 kDa 		No 0
ANXA11-002
ENSP00000404412
ENST00000422982
P50995 [Direct mapping]
Annexin A11
Q5T0G8 [Target identity:100%; Query identity:100%]
Annexin
Show all
Transporters
   Primary Active Transporters
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0006909 [phagocytosis]
GO:0007049 [cell cycle]
GO:0016020 [membrane]
GO:0023026 [MHC class II protein complex binding]
GO:0030496 [midbody]
GO:0042470 [melanosome]
GO:0042581 [specific granule]
GO:0042582 [azurophil granule]
GO:0044548 [S100 protein binding]
GO:0044822 [poly(A) RNA binding]
GO:0045335 [phagocytic vesicle]
GO:0048306 [calcium-dependent protein binding]
GO:0051301 [cell division]
GO:0051592 [response to calcium ion]
GO:0070062 [extracellular exosome]
Show all
 505 aa
54.4 kDa 		No 0
ANXA11-003
ENSP00000398610
ENST00000438331
P50995 [Direct mapping]
Annexin A11
Q5T0G8 [Target identity:100%; Query identity:100%]
Annexin
Show all
Transporters
   Primary Active Transporters
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0006909 [phagocytosis]
GO:0007049 [cell cycle]
GO:0008429 [phosphatidylethanolamine binding]
GO:0016020 [membrane]
GO:0023026 [MHC class II protein complex binding]
GO:0030496 [midbody]
GO:0042470 [melanosome]
GO:0042581 [specific granule]
GO:0042582 [azurophil granule]
GO:0044548 [S100 protein binding]
GO:0044822 [poly(A) RNA binding]
GO:0045335 [phagocytic vesicle]
GO:0048306 [calcium-dependent protein binding]
GO:0051301 [cell division]
GO:0051592 [response to calcium ion]
GO:0070062 [extracellular exosome]
Show all
 505 aa
54.4 kDa 		No 0
ANXA11-006
ENSP00000414642
ENST00000437799
Q5T0G7 [Direct mapping]
Annexin A11
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005544 [calcium-dependent phospholipid binding]
Show all
 150 aa
15 kDa 		No 0
ANXA11-010
ENSP00000405009
ENST00000447489
H0Y6E1 [Direct mapping]
Annexin A11
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005544 [calcium-dependent phospholipid binding]
Show all
 148 aa
16.6 kDa 		No 0
ANXA11-201
ENSP00000265447
ENST00000265447
P50995 [Direct mapping]
Annexin A11
Show all
Transporters
   Primary Active Transporters
Predicted intracellular proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005819 [spindle]
GO:0006909 [phagocytosis]
GO:0007049 [cell cycle]
GO:0016020 [membrane]
GO:0023026 [MHC class II protein complex binding]
GO:0030496 [midbody]
GO:0042470 [melanosome]
GO:0042581 [specific granule]
GO:0042582 [azurophil granule]
GO:0044548 [S100 protein binding]
GO:0044822 [poly(A) RNA binding]
GO:0045335 [phagocytic vesicle]
GO:0048306 [calcium-dependent protein binding]
GO:0051301 [cell division]
GO:0051592 [response to calcium ion]
GO:0070062 [extracellular exosome]
Show all
 472 aa
51.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.