Tissue expression of NAA60 - Summary - The Human Protein Atlas

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NAA60

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	NAA60
Gene description	N(alpha)-acetyltransferase 60, NatF catalytic subunit
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	23
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Not detected
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA040916
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Not detected
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	NAA60 (HGNC Symbol)
Synonyms	FLJ14154, NAT15
Description	N(alpha)-acetyltransferase 60, NatF catalytic subunit (HGNC Symbol)
Entrez gene summary	This gene encodes an enzyme that localizes to the Golgi apparatus, where it transfers an acetyl group to the N-terminus of free proteins. This enzyme acts on histones, and its activity is important for chromatin assembly and chromosome integrity. Alternative splicing and the use of alternative promoters results in multiple transcript variants. The upstream promoter is located in a differentially methylated region (DMR) and undergoes imprinting; transcript variants originating from this position are expressed from the maternal allele. [provided by RefSeq, Nov 2015]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	3443611 - 3486963
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000122390 (version 83.38)
Entrez gene	79903
UniProt	Q9H7X0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H7X0
Antibodypedia	NAA60 antibodies

PROTEIN BROWSER

NAA60-001	NAA60-002	NAA60-003	NAA60-004	NAA60-005	NAA60-006	NAA60-007	NAA60-008	NAA60-009	NAA60-010	NAA60-011	NAA60-012	NAA60-013	NAA60-016	NAA60-017	NAA60-018	NAA60-019	NAA60-023	NAA60-026	NAA60-028	NAA60-029	NAA60-034	NAA60-038

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NAA60-001 ENSP00000385903 ENST00000407558	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008080 [N-acetyltransferase activity] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	242 aa 27.5 kDa	No	0
NAA60-002 ENSP00000401237 ENST00000424546	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008080 [N-acetyltransferase activity] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	249 aa 28.4 kDa	No	0
NAA60-003 ENSP00000354108 ENST00000360862	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008080 [N-acetyltransferase activity] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	177 aa 20.1 kDa	No	0
NAA60-004 ENSP00000405873 ENST00000421765	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	190 aa 20.9 kDa	No	0
NAA60-005 ENSP00000461703 ENST00000576916	I3L153 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all		134 aa 15.1 kDa	No	0
NAA60-006 ENSP00000393224 ENST00000414063	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008080 [N-acetyltransferase activity] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	242 aa 27.5 kDa	No	0
NAA60-007 ENSP00000458667 ENST00000575076	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008080 [N-acetyltransferase activity] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	242 aa 27.5 kDa	No	0
NAA60-008 ENSP00000459057 ENST00000572584	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008080 [N-acetyltransferase activity] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	242 aa 27.5 kDa	No	0
NAA60-009 ENSP00000461730 ENST00000572942	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	179 aa 19.5 kDa	No	0
NAA60-010 ENSP00000459750 ENST00000572757	I3L2K7 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0008080 [N-acetyltransferase activity] GO:0008152 [metabolic process] Show all	141 aa 15.8 kDa	No	0
NAA60-011 ENSP00000458928 ENST00000572169	I3L1L7 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all		109 aa 12.3 kDa	No	0
NAA60-012 ENSP00000459084 ENST00000573593	I3L1T4 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0008080 [N-acetyltransferase activity] GO:0008152 [metabolic process] Show all	129 aa 14.4 kDa	No	0
NAA60-013 ENSP00000461507 ENST00000570372	I3L4T5 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all		80 aa 9.2 kDa	No	0
NAA60-016 ENSP00000461443 ENST00000575733	I3L4Q5 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all		93 aa 10.5 kDa	No	0
NAA60-017 ENSP00000458505 ENST00000573201	I3L115 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all		99 aa 11.2 kDa	No	0
NAA60-018 ENSP00000459275 ENST00000574950	I3L205 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all		106 aa 11.9 kDa	No	0
NAA60-019 ENSP00000459055 ENST00000573580	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008080 [N-acetyltransferase activity] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	177 aa 20.1 kDa	No	0
NAA60-023 ENSP00000459544 ENST00000574328	I3L2B4 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0008080 [N-acetyltransferase activity] GO:0008152 [metabolic process] Show all	120 aa 13.4 kDa	No	0
NAA60-026 ENSP00000459188 ENST00000576787	I3L1X5 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all		77 aa 8.8 kDa	No	0
NAA60-028 ENSP00000459790 ENST00000572131	I3L2M6 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0008080 [N-acetyltransferase activity] GO:0008152 [metabolic process] Show all	121 aa 13.6 kDa	No	0
NAA60-029 ENSP00000458575 ENST00000577013	I3L153 [Direct mapping] N-alpha-acetyltransferase 60 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all		134 aa 15.1 kDa	No	0
NAA60-034 ENSP00000460763 ENST00000570819	Q9H7X0 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Enzymes ENZYME proteins Transferases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0006334 [nucleosome assembly] GO:0007059 [chromosome segregation] GO:0008283 [cell proliferation] GO:0010485 [H4 histone acetyltransferase activity] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0043967 [histone H4 acetylation] Show all	179 aa 19.5 kDa	No	0
NAA60-038 ENSP00000482351 ENST00000615865	A0A087WZ48 [Direct mapping] N-alpha-acetyltransferase 60 Show all	Predicted intracellular proteins Show all		48 aa 5.5 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
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