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Most cancer tissues displayed weak to moderate cytoplasmic positivity, often with a granular pattern. Additional nucleolar staining was observed in several cases. A few cases of melanomas and endometrial cancers were strongly stained. Carcinoids in general were negative.
GENE INFORMATION
Gene name
ZNF644 (HGNC Symbol)
Synonyms
BM-005, KIAA1221, MGC60165, MGC70410
Description
Zinc finger protein 644 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a zinc finger transcription factor that may play a role in eye development. Defects in this gene have been associated with high myopia. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
