Expression of KIAA1549 in cancer - Summary

CANCER ATLAS

Gene description

KIAA1549

Protein class

Cancer-related genes, Disease related genes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA019560

GENE INFORMATION
Gene name	KIAA1549
Synonyms
Description	KIAA1549 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene belongs to the UPF0606 family. This gene has been found to be fused to the BRAF oncogene in many cases of pilocytic astrocytoma. The fusion results from 2Mb tandem duplications at 7q34. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Chromosome	7
Cytoband	q34
Chromosome location (bp)	138831381 - 138981318
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000122778 (version 83.38)
Entrez gene	57670
UniProt	Q9HCM3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HCM3
Antibodypedia	KIAA1549 antibodies

PROTEIN BROWSER

KIAA1549-001	KIAA1549-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KIAA1549-001 ENSP00000406661 ENST00000440172	Q9HCM3 [Direct mapping] UPF0606 protein KIAA1549 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	1934 aa 208.9 kDa	Yes	2
KIAA1549-002 ENSP00000416040 ENST00000422774	Q9HCM3 [Direct mapping] UPF0606 protein KIAA1549 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	1950 aa 210.8 kDa	Yes	2