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Majority of malignant tissues exhibited moderate nuclear immunoreactivity with additional cytoplasmic staining in several cases. A few cases of malignant gliomas, basal cell carcinomas, testicular and colorectal cancers were strongly positive. Most cases of renal, prostate, ovarian and cervical cancers were weakly stained or negative.
GENE INFORMATION
Gene name
RBM19 (HGNC Symbol)
Synonyms
DKFZp586F1023, KIAA0682
Description
RNA binding motif protein 19 (HGNC Symbol)
Entrez gene summary
This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009]