Cell atlas - ACOT9 - The Human Protein Atlas

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ACOT9

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm
	Plasma membrane

Human cell
	Cytosol
	Nucleoplasm
	Plasma Membrane

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GENERAL INFORMATION
Gene name	ACOT9
Gene description	Acyl-CoA thioesterase 9
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane & cytosol. In addition localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved), Cytosol (approved)
Additional location	In addition localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA035533
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane & cytosol. In addition localized to the nucleoplasm.

Main location

Plasma membrane (approved), Cytosol (approved)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA035533	A-431	Plasma membrane
	HPA035533	A-431	Cytosol
	HPA035533	U-2 OS	Nucleoplasm
			Plasma membrane
			Cytosol
	HPA035533	U-251 MG	Nucleoplasm
			Plasma membrane
			Cytosol

GENE INFORMATION
Gene name	ACOT9 (HGNC Symbol)
Synonyms	ACATE2, CGI-16, MT-ACT48
Description	Acyl-CoA thioesterase 9 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a mitochondrial acyl-CoA thioesterase of unknown function. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Chromosome	X
Cytoband	p22.11
Chromosome location (bp)	23702253 - 23766475
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000123130 (version 83.38)
Entrez gene	23597
UniProt	Q9Y305 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y305
Antibodypedia	ACOT9 antibodies

PROTEIN BROWSER

ACOT9-001	ACOT9-004	ACOT9-005	ACOT9-008	ACOT9-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACOT9-001 ENSP00000336580 ENST00000336430	Q9Y305 [Direct mapping] Acyl-coenzyme A thioesterase 9, mitochondrial Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003986 [acetyl-CoA hydrolase activity] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0006637 [acyl-CoA metabolic process] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	439 aa 49.9 kDa	No	0
ACOT9-004 ENSP00000368597 ENST00000379295	Q9Y305 [Direct mapping] Acyl-coenzyme A thioesterase 9, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003986 [acetyl-CoA hydrolase activity] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0006637 [acyl-CoA metabolic process] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	379 aa 43.2 kDa	No	0
ACOT9-005 ENSP00000417778 ENST00000492081	C9J7L8 [Direct mapping] Acyl-coenzyme A thioesterase 9, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		136 aa 15.5 kDa	No	0
ACOT9-008 ENSP00000368605 ENST00000379303	Q9Y305 [Direct mapping] Acyl-coenzyme A thioesterase 9, mitochondrial Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003986 [acetyl-CoA hydrolase activity] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0006637 [acyl-CoA metabolic process] GO:0019432 [triglyceride biosynthetic process] GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	448 aa 50.9 kDa	No	0
ACOT9-009 ENSP00000420490 ENST00000473710	H7C5Q2 [Direct mapping] Acyl-coenzyme A thioesterase 9, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		264 aa 30 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.