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A majority of malignant tissues were negative. Weak cytoplasmic or membranous staining was observed in a few colorectal cancers.
GENE INFORMATION
Gene name
ACTRT1 (HGNC Symbol)
Synonyms
AIP1, ARIP1, Arp-T1, KIAA0705
Description
Actin-related protein T1 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010]
GO:0002230 [positive regulation of defense response to virus by host] GO:0005737 [cytoplasm] GO:0005856 [cytoskeleton] GO:0098779 [mitophagy in response to mitochondrial depolarization]
