Expression of HOXC12 in cancer - Summary

CANCER ATLAS

Gene description

Homeobox C12

Protein class

Plasma proteins, Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA055632

GENE INFORMATION
Gene name	HOXC12 (HGNC Symbol)
Synonyms	HOC3F, HOX3, HOX3F
Description	Homeobox C12 (HGNC Symbol)
Entrez gene summary	This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q13.13
Chromosome location (bp)	53954834 - 53958956
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000123407 (version 83.38)
Entrez gene	3228
UniProt	P31275 (UniProt - Inferred from homology)
neXtProt	NX_P31275
Antibodypedia	HOXC12 antibodies

PROTEIN BROWSER

HOXC12-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HOXC12-001 ENSP00000243103 ENST00000243103	P31275 [Direct mapping] Homeobox protein Hox-C12 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Helix-turn-helix domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0043565 [sequence-specific DNA binding] Show all	282 aa 30.2 kDa	No	0