Expression of ATPAF1 in cancer - Summary

CANCER ATLAS

Gene description

ATP synthase mitochondrial F1 complex assembly factor 1

Protein class

Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA044950

GENE INFORMATION
Gene name	ATPAF1 (HGNC Symbol)
Synonyms	ATP11, Atp11p, FLJ22351
Description	ATP synthase mitochondrial F1 complex assembly factor 1 (HGNC Symbol)
Entrez gene summary	This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 beta subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Aug 2011]
Chromosome	1
Cytoband	p33
Chromosome location (bp)	46632737 - 46673867
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000123472 (version 83.38)
Entrez gene	64756
UniProt	Q5TC12 (UniProt - Evidence at protein level)
neXtProt	NX_Q5TC12
Antibodypedia	ATPAF1 antibodies

PROTEIN BROWSER

ATPAF1-001	ATPAF1-002	ATPAF1-006	ATPAF1-007	ATPAF1-008	ATPAF1-011	ATPAF1-012	ATPAF1-201	ATPAF1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATPAF1-001 ENSP00000460964 ENST00000576409	I3L448 [Direct mapping] ATP synthase mitochondrial F1 complex assembly factor 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006461 [protein complex assembly] Show all	351 aa 38.9 kDa	No	0
ATPAF1-002 ENSP00000431258 ENST00000492233	H0YCA6 [Direct mapping] ATP synthase mitochondrial F1 complex assembly factor 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006461 [protein complex assembly] Show all	113 aa 13 kDa	No	0
ATPAF1-006 ENSP00000330685 ENST00000329231	A8MRA7 [Direct mapping] ATP synthase mitochondrial F1 complex assembly factor 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006461 [protein complex assembly] Show all	283 aa 31.1 kDa	No	0
ATPAF1-007 ENSP00000436690 ENST00000526821	H0YEW4 [Direct mapping] ATP synthase mitochondrial F1 complex assembly factor 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006461 [protein complex assembly] Show all	174 aa 19.9 kDa	No	0
ATPAF1-008 ENSP00000435732 ENST00000532925	Q5TC12 [Direct mapping] ATP synthase mitochondrial F1 complex assembly factor 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0006461 [protein complex assembly] GO:0033615 [mitochondrial proton-transporting ATP synthase complex assembly] Show all	240 aa 27.4 kDa	No	0
ATPAF1-011 ENSP00000432771 ENST00000534216	H0YD21 [Direct mapping] ATP synthase mitochondrial F1 complex assembly factor 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006461 [protein complex assembly] Show all	183 aa 20.7 kDa	No	0
ATPAF1-012 ENSP00000459167 ENST00000574428	Q5TC12 [Direct mapping] ATP synthase mitochondrial F1 complex assembly factor 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0006461 [protein complex assembly] GO:0033615 [mitochondrial proton-transporting ATP synthase complex assembly] Show all	328 aa 36.4 kDa	Yes	0
ATPAF1-201 ENSP00000361005 ENST00000371937	I3L448 [Direct mapping] ATP synthase mitochondrial F1 complex assembly factor 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0006461 [protein complex assembly] Show all	351 aa 38.9 kDa	No	0
ATPAF1-202 ENSP00000443588 ENST00000542495	Q5TC12 [Direct mapping] ATP synthase mitochondrial F1 complex assembly factor 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0006461 [protein complex assembly] GO:0033615 [mitochondrial proton-transporting ATP synthase complex assembly] Show all	177 aa 20.3 kDa	No	0