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Several cases of colorectal, breast and prostate cancers displayed weak to moderate cytoplasmic and occasional nuclear positivity. Remaining malignant cells were in general negative.
Several cases of ovarian cancers displayed moderate to strong cytoplasmic positivity. Malignant carcinoids along with a few cases of breast, endometrial, prostate and colorectal cancers were moderately stained. Remaining malignant cells were weakly stained or negative.
GENE INFORMATION
Gene name
B9D2 (HGNC Symbol)
Synonyms
MGC4093, MKS10
Description
B9 protein domain 2 (HGNC Symbol)
Entrez gene summary
This gene encodes a B9 domain protein, which are exclusively found in ciliated organisms. The gene is upregulated during mucociliary differentiation, and the encoded protein localizes to basal bodies and cilia. Disrupting expression of this gene results in ciliogenesis defects. [provided by RefSeq, Oct 2009]