Expression of MOGAT1 in cancer - Summary

CANCER ATLAS

Gene description

Monoacylglycerol O-acyltransferase 1

Protein class

Enzymes, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA049944

GENE INFORMATION
Gene name	MOGAT1 (HGNC Symbol)
Synonyms	DGAT2L, DGAT2L1, MGAT1
Description	Monoacylglycerol O-acyltransferase 1 (HGNC Symbol)
Entrez gene summary	Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	q36.1
Chromosome location (bp)	222671786 - 222709930
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000124003 (version 83.38)
Entrez gene	116255
UniProt	Q96PD6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96PD6
Antibodypedia	MOGAT1 antibodies

PROTEIN BROWSER

MOGAT1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MOGAT1-001 ENSP00000406674 ENST00000446656	Q96PD6 [Direct mapping] 2-acylglycerol O-acyltransferase 1 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003846 [2-acylglycerol O-acyltransferase activity] GO:0004144 [diacylglycerol O-acyltransferase activity] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006071 [glycerol metabolic process] GO:0006651 [diacylglycerol biosynthetic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups] GO:0019432 [triglyceride biosynthetic process] Show all	335 aa 38.8 kDa	No	1