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Cancer tissues were in most cases weakly stained or negative. Moderate cytoplasmic staining was observed in colorectal, urothelial, pancreatic and liver cancer. Cases of ovarian cancer showed strong positivity.
GENE INFORMATION
Gene name
SDC4 (HGNC Symbol)
Synonyms
amphiglycan, ryudocan, SYND4
Description
Syndecan 4 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]