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PARD6B

CANCER ATLAS

Gene description

 Par-6 family cell polarity regulator beta

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA013376

GENE INFORMATION

Gene name

 PARD6B (HGNC Symbol)

Synonyms

 PAR-6B

Description

 Par-6 family cell polarity regulator beta (HGNC Symbol)

Entrez gene summary

 This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. [provided by RefSeq, Jul 2008]

Chromosome

 20

Cytoband

 q13.13

Chromosome location (bp)

 50731544 - 50756795

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000124171 (version 83.38)

Entrez gene

 84612

UniProt

 Q9BYG5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BYG5

Antibodypedia

 PARD6B antibodies

PROTEIN BROWSER
PARD6B-001
PARD6B-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PARD6B-001
ENSP00000360672
ENST00000371610
Q9BYG5 [Direct mapping]
Partitioning defective 6 homolog beta
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0005938 [cell cortex]
GO:0006461 [protein complex assembly]
GO:0007043 [cell-cell junction assembly]
GO:0007049 [cell cycle]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007409 [axonogenesis]
GO:0030334 [regulation of cell migration]
GO:0034329 [cell junction assembly]
GO:0043234 [protein complex]
GO:0045177 [apical part of cell]
GO:0045216 [cell-cell junction organization]
GO:0051301 [cell division]
GO:0070062 [extracellular exosome]
GO:0070830 [bicellular tight junction assembly]
Show all
 372 aa
41.2 kDa 		No 0
PARD6B-002
ENSP00000379354
ENST00000396039
Q9BYG5 [Direct mapping]
Partitioning defective 6 homolog beta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005923 [bicellular tight junction]
GO:0006461 [protein complex assembly]
GO:0007043 [cell-cell junction assembly]
GO:0007049 [cell cycle]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0007409 [axonogenesis]
GO:0030334 [regulation of cell migration]
GO:0034329 [cell junction assembly]
GO:0045216 [cell-cell junction organization]
GO:0051301 [cell division]
GO:0070062 [extracellular exosome]
GO:0070830 [bicellular tight junction assembly]
Show all
 115 aa
13 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.