Fields »
ABOUT
HELP
BLOG
SNRNP27

GENERAL INFORMATION

Gene name

 SNRNP27

Gene description

 Small nuclear ribonucleoprotein 27kDa (U4/U6.U5)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear and cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA034541
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SNRNP27 (HGNC Symbol)

Synonyms

 RY1

Description

 Small nuclear ribonucleoprotein 27kDa (U4/U6.U5) (HGNC Symbol)

Entrez gene summary

 This gene encodes a serine/arginine-rich (SR) protein. SR proteins play important roles in pre-mRNA splicing by facilitating the recognition and selection of splice sites. The encoded protein associates with the 25S U4/U6.U5 tri-snRNP, a major component of the U2-type spiceosome. The expression of this gene may be altered in cells infected with the human T-cell lymphotropic virus type 1 (HTLV-1) retrovirus. A pseudogene of this gene is located on the long arm of chromosome 5. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

Chromosome

 2

Cytoband

 p13.3

Chromosome location (bp)

 69893560 - 69905575

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000124380 (version 83.38)

Entrez gene

 11017

UniProt

 Q8WVK2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WVK2

Antibodypedia

 SNRNP27 antibodies

PROTEIN BROWSER
SNRNP27-001
SNRNP27-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SNRNP27-001
ENSP00000244227
ENST00000244227
Q8WVK2 [Direct mapping]
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
A8K513 [Target identity:100%; Query identity:100%]
HCG1994066, isoform CRA_a; cDNA FLJ78125, highly similar to Homo sapiens putative nucleic acid binding protein RY-1 (RY1), mRNA; cDNA, FLJ92318, Homo sapiens putative nucleic acid binding protein RY-1 (RY1),mRNA
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0006397 [mRNA processing]
GO:0008150 [biological_process]
GO:0008380 [RNA splicing]
GO:0071011 [precatalytic spliceosome]
Show all
 155 aa
18.9 kDa 		No 0
SNRNP27-002
ENSP00000386608
ENST00000409116
B8ZZ98 [Direct mapping]
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0071011 [precatalytic spliceosome]
Show all
 158 aa
19.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.