Expression of RPP40 in cancer - Summary

CANCER ATLAS

Gene description

Ribonuclease P/MRP 40kDa subunit

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA035685	HPA035686

GENE INFORMATION
Gene name	RPP40 (HGNC Symbol)
Synonyms	bA428J1.3, RNASEP1
Description	Ribonuclease P/MRP 40kDa subunit (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p25.1
Chromosome location (bp)	4994732 - 5004063
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000124787 (version 83.38)
Entrez gene	10799
UniProt	O75818 (UniProt - Evidence at protein level)
neXtProt	NX_O75818
Antibodypedia	RPP40 antibodies

PROTEIN BROWSER

RPP40-001	RPP40-002	RPP40-006	RPP40-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPP40-001 ENSP00000369391 ENST00000380051	O75818 [Direct mapping] Ribonuclease P protein subunit p40 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	363 aa 41.8 kDa	No	0
RPP40-002 ENSP00000317998 ENST00000319533	O75818 [Direct mapping] Ribonuclease P protein subunit p40 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004526 [ribonuclease P activity] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005655 [nucleolar ribonuclease P complex] GO:0008033 [tRNA processing] GO:0010467 [gene expression] GO:0090501 [RNA phosphodiester bond hydrolysis] GO:0090502 [RNA phosphodiester bond hydrolysis, endonucleolytic] Show all	340 aa 39.3 kDa	No	0
RPP40-006 ENSP00000419431 ENST00000464646	X6RLL4 [Direct mapping] Ribonuclease P protein subunit p40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		303 aa 34.7 kDa	No	0
RPP40-201 ENSP00000484334 ENST00000618533	A0A087X1N3 [Direct mapping] Ribonuclease P 40kDa subunit, isoform CRA_c; Ribonuclease P protein subunit p40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		321 aa 36.8 kDa	No	0