Expression of DOK4 in cancer - Summary - The Human Protein Atlas

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DOK4

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TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Docking protein 4

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA055849

GENE INFORMATION
Gene name	DOK4 (HGNC Symbol)
Synonyms	FLJ10488
Description	Docking protein 4 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q21
Chromosome location (bp)	57471922 - 57487327
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125170 (version 83.38)
Entrez gene	55715
UniProt	Q8TEW6 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TEW6
Antibodypedia	DOK4 antibodies

PROTEIN BROWSER

DOK4-001	DOK4-002	DOK4-005	DOK4-006	DOK4-007	DOK4-008	DOK4-009	DOK4-010	DOK4-011	DOK4-012	DOK4-013	DOK4-014	DOK4-015	DOK4-016	DOK4-019

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DOK4-001 ENSP00000344277 ENST00000340099	Q8TEW6 [Direct mapping] Docking protein 4 A0A024R6S2 [Target identity:100%; Query identity:100%] Docking protein 4, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0000165 [MAPK cascade] GO:0005057 [receptor signaling protein activity] GO:0005158 [insulin receptor binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway] GO:0007399 [nervous system development] Show all	326 aa 37 kDa	No	0
DOK4-002 ENSP00000455566 ENST00000566936	H3BQ19 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all	GO:0005158 [insulin receptor binding] Show all	365 aa 41.1 kDa	No	0
DOK4-005 ENSP00000455528 ENST00000567175	H3BPY9 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		54 aa 6.4 kDa	No	0
DOK4-006 ENSP00000457670 ENST00000566588	H3BTI7 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		113 aa 13 kDa	No	0
DOK4-007 ENSP00000456739 ENST00000569538	H3BSK0 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		100 aa 11.5 kDa	No	0
DOK4-008 ENSP00000457971 ENST00000569010	H3BV67 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all	GO:0005158 [insulin receptor binding] Show all	246 aa 28.4 kDa	No	0
DOK4-009 ENSP00000454738 ENST00000566705	H3BN90 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		79 aa 9.2 kDa	No	0
DOK4-010 ENSP00000457621 ENST00000562737	H3BVB4 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		116 aa 13.4 kDa	No	0
DOK4-011 ENSP00000457212 ENST00000567214	H3BTK2 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		103 aa 11.9 kDa	No	0
DOK4-012 ENSP00000457188 ENST00000562008	H3BTI4 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		77 aa 9 kDa	No	0
DOK4-013 ENSP00000458037 ENST00000564378	H3BVB4 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		116 aa 13.4 kDa	No	0
DOK4-014 ENSP00000456590 ENST00000569250	H3BS85 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		122 aa 14 kDa	No	0
DOK4-015 ENSP00000457192 ENST00000568617	H3BTI7 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		113 aa 13 kDa	No	0
DOK4-016 ENSP00000457730 ENST00000567276	H3BTI7 [Direct mapping] Docking protein 4 Show all	Predicted intracellular proteins Show all		113 aa 13 kDa	No	0
DOK4-019 ENSP00000455128 ENST00000569548	Q8TEW6 [Direct mapping] Docking protein 4 A0A024R6S2 [Target identity:100%; Query identity:100%] Docking protein 4, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005158 [insulin receptor binding] GO:0005515 [protein binding] Show all	326 aa 37 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.