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Most malignant cells showed moderate to strong cytoplasmic and nuclear immunoreactivity. Many malignant gliomas and lymphomas were weakly stained or negative.
GENE INFORMATION
Gene name
KIF25 (HGNC Symbol)
Synonyms
KNSL3
Description
Kinesin family member 25 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a member of the kinesin-like protein family. Protein family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. However, the particular function of this gene product has not yet been determined. Two alternatively spliced transcript variants which encode products have been described. Other splice variants have been found that lack exon 2 and the initiation codon for translation. [provided by RefSeq, Jul 2008]