Cell atlas - NPBWR2 - The Human Protein Atlas

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NPBWR2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	NPBWR2
Gene description	Neuropeptides B/W receptor 2
Protein class	G-protein coupled receptors Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	NPBWR2 (HGNC Symbol)
Synonyms	GPR8
Description	Neuropeptides B/W receptor 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain. [provided by RefSeq, Jul 2008]
Chromosome	20
Cytoband	q13.33
Chromosome location (bp)	64105820 - 64107171
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125522 (version 83.38)
Entrez gene	2832
UniProt	P48146 (UniProt - Evidence at protein level)
neXtProt	NX_P48146
Antibodypedia	NPBWR2 antibodies

PROTEIN BROWSER

NPBWR2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NPBWR2-001 ENSP00000358783 ENST00000369768	P48146 [Direct mapping] Neuropeptides B/W receptor type 2 Show all	Transporters G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0004985 [opioid receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007218 [neuropeptide signaling pathway] GO:0007268 [synaptic transmission] GO:0008188 [neuropeptide receptor activity] GO:0016021 [integral component of membrane] GO:0038003 [opioid receptor signaling pathway] GO:0042923 [neuropeptide binding] GO:0043005 [neuron projection] Show all	333 aa 36.9 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.