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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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GTF2F1
  • TISSUE

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

GTF2F1

Gene description

General transcription factor IIF, polypeptide 1, 74kDa

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Mainly nuclear expression in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Approved based on 1 antibody.
HPA022793
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

GTF2F1 (HGNC Symbol)

Synonyms

BTF4, RAP74, TF2F1, TFIIF

Description

General transcription factor IIF, polypeptide 1, 74kDa (HGNC Symbol)

Entrez gene summary

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

6379569 - 6393981

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125651 (version 83.38)

Entrez gene

2962

UniProt

P35269 (UniProt - Evidence at protein level)

neXtProt

NX_P35269

Antibodypedia

GTF2F1 antibodies

PROTEIN BROWSER

GTF2F1-001
GTF2F1-003
GTF2F1-005
GTF2F1-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GTF2F1-001
ENSP00000377969
ENST00000394456
P35269 [Direct mapping]
General transcription factor IIF subunit 1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000398 [mRNA splicing, via spliceosome]
GO:0003677 [DNA binding]
GO:0003713 [transcription coactivator activity]
GO:0003824 [catalytic activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005674 [transcription factor TFIIF complex]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006368 [transcription elongation from RNA polymerase II promoter]
GO:0006370 [7-methylguanosine mRNA capping]
GO:0008134 [transcription factor binding]
GO:0008380 [RNA splicing]
GO:0009615 [response to virus]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019211 [phosphatase activator activity]
GO:0030054 [cell junction]
GO:0032968 [positive regulation of transcription elongation from RNA polymerase II promoter]
GO:0043085 [positive regulation of catalytic activity]
GO:0044822 [poly(A) RNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0050434 [positive regulation of viral transcription]
Show all
517 aa
58.2 kDa
No 0
GTF2F1-003
ENSP00000471542
ENST00000598607
M0R0Z3 [Direct mapping]
General transcription factor IIF subunit 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003824 [catalytic activity]
GO:0005634 [nucleus]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0032968 [positive regulation of transcription elongation from RNA polymerase II promoter]
Show all
127 aa
14.7 kDa
No 0
GTF2F1-005
ENSP00000471403
ENST00000595047
M0R0R9 [Direct mapping]
General transcription factor IIF subunit 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003824 [catalytic activity]
GO:0005634 [nucleus]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0030054 [cell junction]
GO:0032968 [positive regulation of transcription elongation from RNA polymerase II promoter]
Show all
381 aa
43.3 kDa
No 0
GTF2F1-006
ENSP00000469091
ENST00000593678
M0QXD6 [Direct mapping]
General transcription factor IIF subunit 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003824 [catalytic activity]
GO:0005634 [nucleus]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0032968 [positive regulation of transcription elongation from RNA polymerase II promoter]
Show all
433 aa
48.6 kDa
No 0

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The Human Protein Atlas project is funded
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