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SH2D3A

CANCER ATLAS

Gene description

 SH2 domain containing 3A

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA035722

GENE INFORMATION

Gene name

 SH2D3A (HGNC Symbol)

Synonyms

 NSP1

Description

 SH2 domain containing 3A (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.3

Chromosome location (bp)

 6752160 - 6767588

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000125731 (version 83.38)

Entrez gene

 10045

UniProt

 Q9BRG2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BRG2

Antibodypedia

 SH2D3A antibodies

PROTEIN BROWSER
SH2D3A-001
SH2D3A-004
SH2D3A-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SH2D3A-001
ENSP00000245908
ENST00000245908
Q9BRG2 [Direct mapping]
SH2 domain-containing protein 3A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005070 [SH3/SH2 adaptor activity]
GO:0005085 [guanyl-nucleotide exchange factor activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0007254 [JNK cascade]
GO:0007264 [small GTPase mediated signal transduction]
GO:0009967 [positive regulation of signal transduction]
GO:0043547 [positive regulation of GTPase activity]
Show all
 576 aa
63.1 kDa 		No 0
SH2D3A-004
ENSP00000393303
ENST00000437152
Q9BRG2 [Direct mapping]
SH2 domain-containing protein 3A
Show all
   SCAMPI predicted membrane proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005070 [SH3/SH2 adaptor activity]
GO:0005085 [guanyl-nucleotide exchange factor activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0007254 [JNK cascade]
GO:0007264 [small GTPase mediated signal transduction]
GO:0009967 [positive regulation of signal transduction]
GO:0043547 [positive regulation of GTPase activity]
Show all
 483 aa
52.4 kDa 		No 0
SH2D3A-007
ENSP00000470700
ENST00000597687
M0QZQ6 [Direct mapping]
SH2 domain-containing protein 3A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 238 aa
25.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.