Cell atlas - GPCPD1 - The Human Protein Atlas

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GPCPD1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	GPCPD1
Gene description	Glycerophosphocholine phosphodiesterase 1
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Mouse	Localized to the Nucleoplasm in mouse cells.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA042987
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA042987	A-431	Nucleoplasm
	HPA042987	A549	Nucleoplasm
	HPA042987	U-2 OS	Nucleoplasm
	HPA042987	U-2 OS	Plasma membrane

MOUSE CELLS

Main location

Nucleoplasm

Additional location

Vesicles

Mouse gene

ENSMUSG00000027346 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA042987	NIH 3T3	Nucleoplasm
	HPA042987	NIH 3T3	Vesicles

GENE INFORMATION
Gene name	GPCPD1 (HGNC Symbol)
Synonyms	GDE5, GDPD6, KIAA1434
Description	Glycerophosphocholine phosphodiesterase 1 (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	p12.3
Chromosome location (bp)	5544404 - 5611026
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125772 (version 83.38)
Entrez gene	56261
UniProt	Q9NPB8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NPB8
Antibodypedia	GPCPD1 antibodies

PROTEIN BROWSER

GPCPD1-001	GPCPD1-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPCPD1-001 ENSP00000368305 ENST00000379019	Q9NPB8 [Direct mapping] Glycerophosphocholine phosphodiesterase GPCPD1 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006629 [lipid metabolic process] GO:0006644 [phospholipid metabolic process] GO:0007519 [skeletal muscle tissue development] GO:0008081 [phosphoric diester hydrolase activity] GO:0008889 [glycerophosphodiester phosphodiesterase activity] GO:0030246 [carbohydrate binding] GO:0030643 [cellular phosphate ion homeostasis] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] GO:0046475 [glycerophospholipid catabolic process] GO:0047389 [glycerophosphocholine phosphodiesterase activity] GO:2001070 [starch binding] Show all	672 aa 76 kDa	No	0
GPCPD1-004 ENSP00000396720 ENST00000418646	H0Y565 [Direct mapping] Glycerophosphocholine phosphodiesterase GPCPD1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006629 [lipid metabolic process] GO:0008081 [phosphoric diester hydrolase activity] Show all	264 aa 30.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.