Tissue expression of TCF15 - Summary - The Human Protein Atlas

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TCF15

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TCF15
Gene description	Transcription factor 15 (basic helix-loop-helix)
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (adipose tissue, placenta, skeletal muscle, heart muscle, testis)
GTEx:	Tissue enhanced (heart muscle)
FANTOM5:	Tissue enhanced (heart muscle, breast)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA050998
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (adipose tissue, placenta, skeletal muscle, heart muscle, testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (heart muscle)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (heart muscle, breast)

GENE INFORMATION
Gene name	TCF15 (HGNC Symbol)
Synonyms	bHLHa40, EC2, PARAXIS
Description	Transcription factor 15 (basic helix-loop-helix) (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm. The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	603797 - 610398
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125878 (version 83.38)
Entrez gene	6939
UniProt	Q12870 (UniProt - Evidence at transcript level)
neXtProt	NX_Q12870
Antibodypedia	TCF15 antibodies

PROTEIN BROWSER

TCF15-001	TCF15-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TCF15-001 ENSP00000246080 ENST00000246080	Q12870 [Direct mapping] Transcription factor 15 Show all	Predicted intracellular proteins Transcription factors Basic domains Show all	GO:0001756 [somitogenesis] GO:0003016 [respiratory system process] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007498 [mesoderm development] GO:0007517 [muscle organ development] GO:0009952 [anterior/posterior pattern specification] GO:0010468 [regulation of gene expression] GO:0036342 [post-anal tail morphogenesis] GO:0042755 [eating behavior] GO:0043583 [ear development] GO:0043588 [skin development] GO:0045198 [establishment of epithelial cell apical/basal polarity] GO:0046983 [protein dimerization activity] GO:0048339 [paraxial mesoderm development] GO:0048644 [muscle organ morphogenesis] GO:0048705 [skeletal system morphogenesis] GO:0050884 [neuromuscular process controlling posture] GO:0060231 [mesenchymal to epithelial transition] GO:1903053 [regulation of extracellular matrix organization] Show all	199 aa 20.8 kDa	No	0
TCF15-201 ENSP00000483116 ENST00000621005	A0A087X058 [Direct mapping] Transcription factor 15 Show all	Predicted intracellular proteins Show all	GO:0046983 [protein dimerization activity] Show all	198 aa 20.8 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.