Expression of TMEM115 in cancer - Summary

CANCER ATLAS

Gene description

Transmembrane protein 115

Protein class

Plasma proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA015497	CAB006319

GENE INFORMATION
Gene name	TMEM115 (HGNC Symbol)
Synonyms	PL6
Description	Transmembrane protein 115 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	p21.31
Chromosome location (bp)	50354749 - 50359610
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126062 (version 83.38)
Entrez gene	11070
UniProt	Q12893 (UniProt - Evidence at protein level)
neXtProt	NX_Q12893
Antibodypedia	TMEM115 antibodies

PROTEIN BROWSER

TMEM115-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM115-001 ENSP00000266025 ENST00000266025	Q12893 [Direct mapping] Transmembrane protein 115 A0A024R2Y2 [Target identity:100%; Query identity:100%] Transmembrane protein 115, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005794 [Golgi apparatus] GO:0006486 [protein glycosylation] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0008285 [negative regulation of cell proliferation] GO:0015031 [protein transport] GO:0016021 [integral component of membrane] GO:0017119 [Golgi transport complex] GO:0032580 [Golgi cisterna membrane] GO:0042802 [identical protein binding] Show all	351 aa 38.2 kDa	No	7