Expression of ST3GAL3 in cancer - Summary

CANCER ATLAS

Gene description

ST3 beta-galactoside alpha-2,3-sialyltransferase 3

Protein class

Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA051102

GENE INFORMATION
Gene name	ST3GAL3 (HGNC Symbol)
Synonyms	MRT12, SIAT6
Description	ST3 beta-galactoside alpha-2,3-sialyltransferase 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with autosomal recessive nonsymdromic mental retardation-12 (MRT12). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
Chromosome	1
Cytoband	p34.1
Chromosome location (bp)	43705824 - 43931165
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126091 (version 83.38)
Entrez gene	6487
UniProt	Q11203 (UniProt - Evidence at protein level)
neXtProt	NX_Q11203
Antibodypedia	ST3GAL3 antibodies

PROTEIN BROWSER

ST3GAL3-001	ST3GAL3-002	ST3GAL3-003	ST3GAL3-004	ST3GAL3-005	ST3GAL3-006	ST3GAL3-007	ST3GAL3-008	ST3GAL3-009	ST3GAL3-010	ST3GAL3-011	ST3GAL3-012	ST3GAL3-017	ST3GAL3-024	ST3GAL3-025	ST3GAL3-026	ST3GAL3-027	ST3GAL3-033	ST3GAL3-034	ST3GAL3-201	ST3GAL3-202	ST3GAL3-203	ST3GAL3-204	ST3GAL3-205	ST3GAL3-206	ST3GAL3-207

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ST3GAL3-001 ENSP00000355341 ENST00000361392	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	375 aa 42.2 kDa	No	2
ST3GAL3-002 ENSP00000354748 ENST00000361400	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	359 aa 40.6 kDa	No	2
ST3GAL3-003 ENSP00000361444 ENST00000372369	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	345 aa 38.7 kDa	No	2
ST3GAL3-004 ENSP00000354657 ENST00000361746	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	444 aa 49.6 kDa	No	2
ST3GAL3-005 ENSP00000361442 ENST00000372367	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	201 aa 22.6 kDa	No	1
ST3GAL3-006 ENSP00000317192 ENST00000347631	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	390 aa 43.8 kDa	No	2
ST3GAL3-007 ENSP00000355201 ENST00000361812	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	170 aa 19 kDa	No	1
ST3GAL3-008 ENSP00000361441 ENST00000372366	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	185 aa 20.9 kDa	No	1
ST3GAL3-009 ENSP00000361440 ENST00000372365	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	186 aa 20.8 kDa	No	1
ST3GAL3-010 ENSP00000361443 ENST00000372368	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	429 aa 48 kDa	No	2
ST3GAL3-011 ENSP00000361447 ENST00000372372	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	413 aa 46.5 kDa	No	2
ST3GAL3-012 ENSP00000361437 ENST00000372362	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	155 aa 17.4 kDa	No	1
ST3GAL3-017 ENSP00000435603 ENST00000531451	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	139 aa 15.9 kDa	No	1
ST3GAL3-024 ENSP00000436298 ENST00000490502	H0YEP7 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0005794 [Golgi apparatus] GO:0006486 [protein glycosylation] GO:0008373 [sialyltransferase activity] GO:0016021 [integral component of membrane] GO:0097503 [sialylation] Show all	197 aa 21.9 kDa	No	0
ST3GAL3-025 ENSP00000434876 ENST00000528371	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	186 aa 21 kDa	No	1
ST3GAL3-026 ENSP00000432682 ENST00000531993	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	261 aa 30 kDa	No	1
ST3GAL3-027 ENSP00000432965 ENST00000533933	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	277 aa 31.6 kDa	No	1
ST3GAL3-033 ENSP00000329755 ENST00000332628	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	344 aa 38.9 kDa	No	2
ST3GAL3-034 ENSP00000434378 ENST00000531816	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	101 aa 11.4 kDa	No	1
ST3GAL3-201 ENSP00000262915 ENST00000262915	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	444 aa 49.6 kDa	No	2
ST3GAL3-202 ENSP00000333494 ENST00000330208	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	101 aa 11.4 kDa	No	1
ST3GAL3-203 ENSP00000335633 ENST00000335430	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	185 aa 20.9 kDa	No	1
ST3GAL3-204 ENSP00000316999 ENST00000351035	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	413 aa 46.5 kDa	No	2
ST3GAL3-205 ENSP00000330463 ENST00000353126	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	277 aa 31.6 kDa	No	1
ST3GAL3-206 ENSP00000361449 ENST00000372374	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006486 [protein glycosylation] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0008373 [sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	344 aa 38.9 kDa	No	2
ST3GAL3-207 ENSP00000439634 ENST00000545417	Q11203 [Direct mapping] CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0000139 [Golgi membrane] GO:0001574 [ganglioside biosynthetic process] GO:0003836 [beta-galactoside (CMP) alpha-2,3-sialyltransferase activity] GO:0005576 [extracellular region] GO:0005975 [carbohydrate metabolic process] GO:0006488 [dolichol-linked oligosaccharide biosynthetic process] GO:0006493 [protein O-linked glycosylation] GO:0008118 [N-acetyllactosaminide alpha-2,3-sialyltransferase activity] GO:0009311 [oligosaccharide metabolic process] GO:0016266 [O-glycan processing] GO:0018146 [keratan sulfate biosynthetic process] GO:0018279 [protein N-linked glycosylation via asparagine] GO:0030173 [integral component of Golgi membrane] GO:0030203 [glycosaminoglycan metabolic process] GO:0032580 [Golgi cisterna membrane] GO:0042339 [keratan sulfate metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0044281 [small molecule metabolic process] GO:0097503 [sialylation] Show all	170 aa 19 kDa	No	1