Fields »
ABOUT
HELP
BLOG
PCID2

GENERAL INFORMATION

Gene name

 PCID2

Gene description

 PCI domain containing 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Granular cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA069107
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 PCID2 (HGNC Symbol)

Synonyms

 FLJ11305

Description

 PCI domain containing 2 (HGNC Symbol)

Entrez gene summary

 PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2 (MAD2L1; MIM 601467) (Nakaya et al., 2010 [PubMed 20870947]).[supplied by OMIM, Jan 2011]

Chromosome

 13

Cytoband

 q34

Chromosome location (bp)

 113177539 - 113208715

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000126226 (version 83.38)

Entrez gene

 55795

UniProt

 Q5JVF3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5JVF3

Antibodypedia

 PCID2 antibodies

PROTEIN BROWSER
PCID2-001
PCID2-002
PCID2-003
PCID2-005
PCID2-007
PCID2-009
PCID2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PCID2-001
ENSP00000364628
ENST00000375479
Q5JVF3 [Direct mapping]
PCI domain-containing protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0043066 [negative regulation of apoptotic process]
GO:0043488 [regulation of mRNA stability]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048536 [spleen development]
GO:0090267 [positive regulation of mitotic cell cycle spindle assembly checkpoint]
GO:2000117 [negative regulation of cysteine-type endopeptidase activity]
Show all
 399 aa
46 kDa 		No 0
PCID2-002
ENSP00000337405
ENST00000337344
Q5JVF3 [Direct mapping]
PCI domain-containing protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0043066 [negative regulation of apoptotic process]
GO:0043488 [regulation of mRNA stability]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048536 [spleen development]
GO:0090267 [positive regulation of mitotic cell cycle spindle assembly checkpoint]
GO:2000117 [negative regulation of cysteine-type endopeptidase activity]
Show all
 399 aa
46 kDa 		No 0
PCID2-003
ENSP00000246505
ENST00000246505
Q5JVF3 [Direct mapping]
PCI domain-containing protein 2
A0A024RE04 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0043066 [negative regulation of apoptotic process]
GO:0043488 [regulation of mRNA stability]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048536 [spleen development]
GO:0090267 [positive regulation of mitotic cell cycle spindle assembly checkpoint]
GO:2000117 [negative regulation of cysteine-type endopeptidase activity]
Show all
 453 aa
52.1 kDa 		No 0
PCID2-005
ENSP00000364606
ENST00000375457
Q5JVF3 [Direct mapping]
PCI domain-containing protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0043066 [negative regulation of apoptotic process]
GO:0043488 [regulation of mRNA stability]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048536 [spleen development]
GO:0090267 [positive regulation of mitotic cell cycle spindle assembly checkpoint]
GO:2000117 [negative regulation of cysteine-type endopeptidase activity]
Show all
 397 aa
45.8 kDa 		No 0
PCID2-007
ENSP00000364626
ENST00000375477
Q5JVF3 [Direct mapping]
PCI domain-containing protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0043066 [negative regulation of apoptotic process]
GO:0043488 [regulation of mRNA stability]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048536 [spleen development]
GO:0090267 [positive regulation of mitotic cell cycle spindle assembly checkpoint]
GO:2000117 [negative regulation of cysteine-type endopeptidase activity]
Show all
 399 aa
46 kDa 		No 0
PCID2-009
ENSP00000364608
ENST00000375459
Q5JVF3 [Direct mapping]
PCI domain-containing protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0043066 [negative regulation of apoptotic process]
GO:0043488 [regulation of mRNA stability]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048536 [spleen development]
GO:0090267 [positive regulation of mitotic cell cycle spindle assembly checkpoint]
GO:2000117 [negative regulation of cysteine-type endopeptidase activity]
Show all
 397 aa
45.8 kDa 		No 0
PCID2-201
ENSP00000479494
ENST00000622406
Q5JVF3 [Direct mapping]
PCI domain-containing protein 2
A0A024RE04 [Target identity:100%; Query identity:100%]
Uncharacterized protein
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005575 [cellular_component]
GO:0043066 [negative regulation of apoptotic process]
GO:0043488 [regulation of mRNA stability]
GO:0045579 [positive regulation of B cell differentiation]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048536 [spleen development]
GO:0090267 [positive regulation of mitotic cell cycle spindle assembly checkpoint]
GO:2000117 [negative regulation of cysteine-type endopeptidase activity]
Show all
 453 aa
52.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.