Tissue expression of STATH - Summary - The Human Protein Atlas

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STATH

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TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	STATH
Gene description	Statherin
Protein class	Plasma proteins Predicted secreted proteins Transporters
Predicted localization	Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (salivary gland)
GTEx:	Tissue enriched (salivary gland)
FANTOM5:	Tissue enriched (salivary gland)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression as well as extracellular positivity in salivary gland.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA044569
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (salivary gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (salivary gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (salivary gland)

GENE INFORMATION
Gene name	STATH (HGNC Symbol)
Synonyms	STR
Description	Statherin (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	q13.3
Chromosome location (bp)	69995930 - 70002570
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126549 (version 83.38)
Entrez gene	6779
UniProt	P02808 (UniProt - Evidence at protein level)
neXtProt	NX_P02808
Antibodypedia	STATH antibodies

PROTEIN BROWSER

STATH-001	STATH-003	STATH-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STATH-001 ENSP00000246895 ENST00000246895	P02808 [Direct mapping] Statherin Show all	Transporters Transporter channels and pores MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001503 [ossification] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0030197 [extracellular matrix constituent, lubricant activity] GO:0030345 [structural constituent of tooth enamel] GO:0030500 [regulation of bone mineralization] GO:0030502 [negative regulation of bone mineralization] GO:0031214 [biomineral tissue development] GO:0042742 [defense response to bacterium] GO:0046541 [saliva secretion] GO:0046848 [hydroxyapatite binding] Show all	62 aa 7.3 kDa	Yes	0
STATH-003 ENSP00000370448 ENST00000381060	P02808 [Direct mapping] Statherin Show all	Transporters Transporter channels and pores MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001503 [ossification] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0030197 [extracellular matrix constituent, lubricant activity] GO:0030345 [structural constituent of tooth enamel] GO:0030500 [regulation of bone mineralization] GO:0030502 [negative regulation of bone mineralization] GO:0031214 [biomineral tissue development] GO:0042742 [defense response to bacterium] GO:0046541 [saliva secretion] GO:0046848 [hydroxyapatite binding] Show all	52 aa 6.1 kDa	Yes	0
STATH-201 ENSP00000484341 ENST00000615994	P02808 [Direct mapping] Statherin Show all	Transporters Transporter channels and pores MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001503 [ossification] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0030197 [extracellular matrix constituent, lubricant activity] GO:0030345 [structural constituent of tooth enamel] GO:0030500 [regulation of bone mineralization] GO:0030502 [negative regulation of bone mineralization] GO:0031214 [biomineral tissue development] GO:0042742 [defense response to bacterium] GO:0046541 [saliva secretion] GO:0046848 [hydroxyapatite binding] Show all	62 aa 7.3 kDa	Yes	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.