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Most cancer cells showed moderate to strong cytoplasmic and nuclear positivity. Positive nuclear and/or cytoplasmic and membranous staining in adenocarcinomas i.e. of the breast, ovary and prostate, squamous cell and urothelial carcinomas.
GENE INFORMATION
Gene name
RHOJ (HGNC Symbol)
Synonyms
ARHJ, FLJ14445, RASL7B, TCL
Description
Ras homolog family member J (HGNC Symbol)
Entrez gene summary
This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011]