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NXF5

GENERAL INFORMATION

Gene name

 NXF5

Gene description

 Nuclear RNA export factor 5

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Not detected
GTEx:Not detected

Protein evidence

 Evidence at transcript level

Protein expression

 Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene.

Reliability score

 Uncertain based on 1 antibody.
HPA002079
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
Cerebral cortexThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSkin0246810TPM
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
HypothalamusPituitary glandCerebral cortexHippocampusCaudateCerebellumThyroid glandAdrenal glandSpleenHeart muscleSkeletal muscleLungLiverPancreasSalivary glandEsophagusStomachSmall intestineColonKidneyUrinary bladderTestisProstateBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryAdipose tissueSkin0246810RPKM

GENE INFORMATION

Gene name

 NXF5

Synonyms

Description

 Nuclear RNA export factor 5 (HGNC Symbol)

Entrez gene summary

 This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo. [provided by RefSeq, Jul 2009]

Chromosome

 X

Cytoband

 q22.1

Chromosome location (bp)

 101832112 - 101857577

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000126952 (version 83.38)

Entrez gene

 55998

UniProt

 Q9H1B4 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9H1B4

Antibodypedia

 NXF5 antibodies

PROTEIN BROWSER
NXF5-007
NXF5-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NXF5-007
ENSP00000426978
ENST00000473265
Q9H1B4 [Direct mapping]
Nuclear RNA export factor 5
Show all
Predicted intracellular proteins
Disease related genes
Show all
GO:0000166 [nucleotide binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006406 [mRNA export from nucleus]
GO:0007275 [multicellular organismal development]
GO:0016973 [poly(A)+ mRNA export from nucleus]
GO:0044822 [poly(A) RNA binding]
GO:0050658 [RNA transport]
Show all
 365 aa
42.2 kDa 		No 0
NXF5-201
ENSP00000442401
ENST00000537026
Q9H1B4 [Direct mapping]
Nuclear RNA export factor 5
Show all
Predicted intracellular proteins
Disease related genes
Show all
GO:0000166 [nucleotide binding]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006406 [mRNA export from nucleus]
GO:0007275 [multicellular organismal development]
GO:0016973 [poly(A)+ mRNA export from nucleus]
GO:0044822 [poly(A) RNA binding]
GO:0050658 [RNA transport]
Show all
 397 aa
45.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.