Expression of HP1BP3 in cancer - Summary

CANCER ATLAS

Gene description

Heterochromatin protein 1, binding protein 3

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA028215

GENE INFORMATION
Gene name	HP1BP3 (HGNC Symbol)
Synonyms	HP1-BP74
Description	Heterochromatin protein 1, binding protein 3 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.12
Chromosome location (bp)	20742661 - 20787323
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000127483 (version 83.38)
Entrez gene	50809
UniProt	Q5SSJ5 (UniProt - Evidence at protein level)
neXtProt	NX_Q5SSJ5
Antibodypedia	HP1BP3 antibodies

PROTEIN BROWSER

HP1BP3-001	HP1BP3-003	HP1BP3-004	HP1BP3-005	HP1BP3-006	HP1BP3-010	HP1BP3-011	HP1BP3-012	HP1BP3-013	HP1BP3-014	HP1BP3-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HP1BP3-001 ENSP00000312625 ENST00000312239	Q5SSJ5 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005694 [chromosome] GO:0006334 [nucleosome assembly] GO:0006355 [regulation of transcription, DNA-templated] GO:0031491 [nucleosome binding] GO:0042127 [regulation of cell proliferation] GO:0070828 [heterochromatin organization] GO:0071456 [cellular response to hypoxia] GO:0097298 [regulation of nucleus size] Show all	553 aa 61.2 kDa	No	0
HP1BP3-003 ENSP00000364139 ENST00000375000	Q5SSJ5 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005694 [chromosome] GO:0006334 [nucleosome assembly] GO:0006355 [regulation of transcription, DNA-templated] GO:0031491 [nucleosome binding] GO:0042127 [regulation of cell proliferation] GO:0070828 [heterochromatin organization] GO:0071456 [cellular response to hypoxia] GO:0097298 [regulation of nucleus size] Show all	133 aa 14.6 kDa	No	0
HP1BP3-004 ENSP00000364142 ENST00000375003	Q5SSJ5 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005694 [chromosome] GO:0006334 [nucleosome assembly] GO:0006355 [regulation of transcription, DNA-templated] GO:0031491 [nucleosome binding] GO:0042127 [regulation of cell proliferation] GO:0070828 [heterochromatin organization] GO:0071456 [cellular response to hypoxia] GO:0097298 [regulation of nucleus size] Show all	401 aa 44.4 kDa	No	0
HP1BP3-005 ENSP00000403039 ENST00000438032	X6RGJ2 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	327 aa 36.5 kDa	No	0
HP1BP3-006 ENSP00000402754 ENST00000424732	Q5SWC8 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	278 aa 31.5 kDa	No	0
HP1BP3-010 ENSP00000405362 ENST00000414993	B0QZK9 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		76 aa 8.2 kDa	No	0
HP1BP3-011 ENSP00000397656 ENST00000419490	B0QZK5 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		40 aa 4.4 kDa	No	0
HP1BP3-012 ENSP00000402096 ENST00000437575	B0QZK6 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		45 aa 5.1 kDa	No	0
HP1BP3-013 ENSP00000401874 ENST00000443615	B0QZK7 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		19 aa 2.2 kDa	No	0
HP1BP3-014 ENSP00000391281 ENST00000417710	B0QZK8 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		124 aa 13.7 kDa	No	0
HP1BP3-015 ENSP00000391721 ENST00000419948	B0QZK4 [Direct mapping] Heterochromatin protein 1-binding protein 3 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	253 aa 28.5 kDa	No	0