Cell atlas - WFIKKN1 - The Human Protein Atlas

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WFIKKN1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	WFIKKN1
Gene description	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (EFO-21, NTERA-2)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (EFO-21, NTERA-2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	WFIKKN1 (HGNC Symbol)
Synonyms	C16orf12, RJD2, WFDC20A, WFIKKN
Description	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases. [provided by RefSeq, Jul 2008]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	629239 - 634116
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000127578 (version 83.38)
Entrez gene	117166
UniProt	Q96NZ8 (UniProt - Evidence at protein level)
neXtProt	NX_Q96NZ8
Antibodypedia	WFIKKN1 antibodies

PROTEIN BROWSER

WFIKKN1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
WFIKKN1-001 ENSP00000324763 ENST00000319070	Q96NZ8 [Direct mapping] WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0001501 [skeletal system development] GO:0004867 [serine-type endopeptidase inhibitor activity] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0008191 [metalloendopeptidase inhibitor activity] GO:0010951 [negative regulation of endopeptidase activity] GO:0030414 [peptidase inhibitor activity] GO:0032091 [negative regulation of protein binding] GO:0043392 [negative regulation of DNA binding] GO:0048747 [muscle fiber development] GO:0060021 [palate development] Show all	548 aa 58.8 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.