Expression of GNAZ in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Guanine nucleotide binding protein (G protein), alpha z polypeptide

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA003011

GENE INFORMATION
Gene name	GNAZ
Synonyms
Description	Guanine nucleotide binding protein (G protein), alpha z polypeptide (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008]
Chromosome	22
Cytoband
Chromosome location (bp)	23070361 - 23125037
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000128266 (version 83.38)
Entrez gene	2781
UniProt	P19086 (UniProt - Evidence at transcript level)
neXtProt	NX_P19086
Antibodypedia	GNAZ antibodies

PROTEIN BROWSER

GNAZ-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GNAZ-001 ENSP00000478892 ENST00000615612	P19086 [Direct mapping] Guanine nucleotide-binding protein G(z) subunit alpha Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0004871 [signal transducer activity] GO:0005057 [receptor signaling protein activity] GO:0005525 [GTP binding] GO:0005635 [nuclear envelope] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007188 [adenylate cyclase-modulating G-protein coupled receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0008152 [metabolic process] GO:0019001 [guanyl nucleotide binding] GO:0031683 [G-protein beta/gamma-subunit complex binding] GO:0031821 [G-protein coupled serotonin receptor binding] GO:0035556 [intracellular signal transduction] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	355 aa 40.9 kDa	No	0