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Most cancer cells exhibited weak to moderate cytoplasmic immunoreactivity. Cases of testicular and endometrial cancers showed strong staining. Several gastric cancers, gliomas and lymphomas were negative.
GENE INFORMATION
Gene name
TPST2 (HGNC Symbol)
Synonyms
TANGO13B
Description
Tyrosylprotein sulfotransferase 2 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]