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APOBEC3F

GENERAL INFORMATION

Gene name

 APOBEC3F

Gene description

 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 APOBEC3F (HGNC Symbol)

Synonyms

 ARP8, BK150C2.4.MRNA, KA6

Description

 Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F (HGNC Symbol)

Entrez gene summary

 This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

 22

Cytoband

 q13.1

Chromosome location (bp)

 39040604 - 39053910

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000128394 (version 83.38)

Entrez gene

 200316

UniProt

 Q8IUX4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8IUX4

Antibodypedia

 APOBEC3F antibodies

PROTEIN BROWSER
APOBEC3F-001
APOBEC3F-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
APOBEC3F-001
ENSP00000309749
ENST00000308521
Q8IUX4 [Direct mapping]
DNA dC->dU-editing enzyme APOBEC-3F
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000932 [cytoplasmic mRNA processing body]
GO:0002230 [positive regulation of defense response to virus by host]
GO:0003723 [RNA binding]
GO:0003824 [catalytic activity]
GO:0004126 [cytidine deaminase activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0009972 [cytidine deamination]
GO:0010529 [negative regulation of transposition]
GO:0016553 [base conversion or substitution editing]
GO:0016787 [hydrolase activity]
GO:0016814 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines]
GO:0030529 [ribonucleoprotein complex]
GO:0030895 [apolipoprotein B mRNA editing enzyme complex]
GO:0044822 [poly(A) RNA binding]
GO:0045071 [negative regulation of viral genome replication]
GO:0045087 [innate immune response]
GO:0045869 [negative regulation of single stranded viral RNA replication via double stranded DNA intermediate]
GO:0048525 [negative regulation of viral process]
GO:0051607 [defense response to virus]
GO:0070383 [DNA cytosine deamination]
GO:0080111 [DNA demethylation]
Show all
 373 aa
45 kDa 		No 0
APOBEC3F-002
ENSP00000370977
ENST00000381565
Q8IUX4 [Direct mapping]
DNA dC->dU-editing enzyme APOBEC-3F
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000932 [cytoplasmic mRNA processing body]
GO:0002230 [positive regulation of defense response to virus by host]
GO:0003723 [RNA binding]
GO:0004126 [cytidine deaminase activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0009972 [cytidine deamination]
GO:0010529 [negative regulation of transposition]
GO:0016553 [base conversion or substitution editing]
GO:0030529 [ribonucleoprotein complex]
GO:0030895 [apolipoprotein B mRNA editing enzyme complex]
GO:0044822 [poly(A) RNA binding]
GO:0045071 [negative regulation of viral genome replication]
GO:0045087 [innate immune response]
GO:0045869 [negative regulation of single stranded viral RNA replication via double stranded DNA intermediate]
GO:0048525 [negative regulation of viral process]
GO:0051607 [defense response to virus]
GO:0070383 [DNA cytosine deamination]
GO:0080111 [DNA demethylation]
Show all
 101 aa
11.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.