Expression of DNAJB9 in cancer - Summary

CANCER ATLAS

Gene description

DnaJ (Hsp40) homolog, subfamily B, member 9

Protein class

Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA040967	HPA041553

GENE INFORMATION
Gene name	DNAJB9 (HGNC Symbol)
Synonyms	MDG1
Description	DnaJ (Hsp40) homolog, subfamily B, member 9 (HGNC Symbol)
Entrez gene summary	This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. This gene is a member of the type 2 subgroup of DnaJ proteins. The encoded protein is localized to the endoplasmic reticulum. This protein is induced by endoplasmic reticulum stress and plays a role in protecting stressed cells from apoptosis. [provided by RefSeq, Dec 2010]
Chromosome	7
Cytoband	q31.1
Chromosome location (bp)	108569568 - 108574850
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000128590 (version 83.38)
Entrez gene	4189
UniProt	Q9UBS3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UBS3
Antibodypedia	DNAJB9 antibodies

PROTEIN BROWSER

DNAJB9-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DNAJB9-001 ENSP00000249356 ENST00000249356	Q9UBS3 [Direct mapping] DnaJ homolog subfamily B member 9 Q6FIF1 [Target identity:100%; Query identity:100%] DNAJB9 protein; DnaJ (Hsp40) homolog, subfamily B, member 9; DnaJ (Hsp40) homolog, subfamily B, member 9, isoform CRA_b; MSTP049; cDNA FLJ34885 fis, clone NT2NE2016608, highly similar to DnaJ homolog subfamily B member 9 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005788 [endoplasmic reticulum lumen] GO:0005789 [endoplasmic reticulum membrane] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0044267 [cellular protein metabolic process] GO:0051787 [misfolded protein binding] GO:0070062 [extracellular exosome] Show all	223 aa 25.5 kDa	Yes	0