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HOXD9

GENERAL INFORMATION

Gene name

 HOXD9

Gene description

 Homeobox D9

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (endometrium)
GTEx:Tissue enhanced (endometrium)
FANTOM5:Tissue enhanced (endometrium)

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (endometrium)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (endometrium)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (endometrium)

GENE INFORMATION

Gene name

 HOXD9 (HGNC Symbol)

Synonyms

 HOX4, HOX4C

Description

 Homeobox D9 (HGNC Symbol)

Entrez gene summary

 This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 q31.1

Chromosome location (bp)

 176122720 - 176124937

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000128709 (version 83.38)

Entrez gene

 3235

UniProt

 P28356 (UniProt - Evidence at protein level)

neXtProt

 NX_P28356

Antibodypedia

 HOXD9 antibodies

PROTEIN BROWSER
HOXD9-001
HOXD9-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HOXD9-001
ENSP00000249499
ENST00000249499
P28356 [Direct mapping]
Homeobox protein Hox-D9
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001227 [transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007338 [single fertilization]
GO:0007519 [skeletal muscle tissue development]
GO:0008344 [adult locomotory behavior]
GO:0009952 [anterior/posterior pattern specification]
GO:0009954 [proximal/distal pattern formation]
GO:0010468 [regulation of gene expression]
GO:0030879 [mammary gland development]
GO:0035115 [embryonic forelimb morphogenesis]
GO:0035136 [forelimb morphogenesis]
GO:0035137 [hindlimb morphogenesis]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048704 [embryonic skeletal system morphogenesis]
GO:0048706 [embryonic skeletal system development]
GO:0048935 [peripheral nervous system neuron development]
Show all
 352 aa
36.5 kDa 		No 0
HOXD9-201
ENSP00000484642
ENST00000613849
A0A087X222 [Direct mapping]
Homeobox protein Hox-D9
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
Show all
 341 aa
35.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.