Expression of TWSG1 in cancer - Summary

CANCER ATLAS

Gene description

Twisted gastrulation BMP signaling modulator 1

Protein class

Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA014898

GENE INFORMATION
Gene name	TWSG1 (HGNC Symbol)
Synonyms	TSG
Description	Twisted gastrulation BMP signaling modulator 1 (HGNC Symbol)
Entrez gene summary
Chromosome	18
Cytoband	p11.22
Chromosome location (bp)	9334767 - 9402420
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000128791 (version 83.38)
Entrez gene	57045
UniProt	Q9GZX9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9GZX9
Antibodypedia	TWSG1 antibodies

PROTEIN BROWSER

TWSG1-001	TWSG1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TWSG1-001 ENSP00000262120 ENST00000262120	Q9GZX9 [Direct mapping] Twisted gastrulation protein homolog 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001503 [ossification] GO:0001707 [mesoderm formation] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0007435 [salivary gland morphogenesis] GO:0009888 [tissue development] GO:0030097 [hemopoiesis] GO:0030154 [cell differentiation] GO:0030509 [BMP signaling pathway] GO:0030513 [positive regulation of BMP signaling pathway] GO:0030514 [negative regulation of BMP signaling pathway] GO:0030900 [forebrain development] GO:0043010 [camera-type eye development] GO:0045668 [negative regulation of osteoblast differentiation] GO:0070062 [extracellular exosome] Show all	223 aa 25 kDa	Yes	0
TWSG1-003 ENSP00000464458 ENST00000581641	J3QS03 [Direct mapping] Twisted gastrulation protein homolog 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		184 aa 20.4 kDa	Yes	0