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INO80

GENERAL INFORMATION

Gene name

 INO80

Gene description

 INO80 complex subunit

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 INO80 (HGNC Symbol)

Synonyms

 hINO80, Ino80, INO80A, INOC1, KIAA1259

Description

 INO80 complex subunit (HGNC Symbol)

Entrez gene summary

 This gene encodes a subunit of the chromatin remodeling complex, which is classified into subfamilies depending on sequence features apart from the conserved ATPase domain. This protein is the catalytic ATPase subunit of the INO80 chromatin remodeling complex, which is characterized by a DNA-binding domain. This protein is proposed to bind DNA and be recruited by the YY1 transcription factor to activate certain genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Chromosome

 15

Cytoband

 q15.1

Chromosome location (bp)

 40978880 - 41116354

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000128908 (version 83.38)

Entrez gene

 54617

UniProt

 Q9ULG1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9ULG1

Antibodypedia

 INO80 antibodies

PROTEIN BROWSER
INO80-001
INO80-201
INO80-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
INO80-001
ENSP00000355205
ENST00000361937
Q9ULG1 [Direct mapping]
DNA helicase INO80
A0A024R9R7 [Target identity:100%; Query identity:100%]
INO80 complex homolog 1 (S. cerevisiae), isoform CRA_b
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000724 [double-strand break repair via homologous recombination]
GO:0003677 [DNA binding]
GO:0003678 [DNA helicase activity]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005874 [microtubule]
GO:0006302 [double-strand break repair]
GO:0006338 [chromatin remodeling]
GO:0010571 [positive regulation of nuclear cell cycle DNA replication]
GO:0016817 [hydrolase activity, acting on acid anhydrides]
GO:0016887 [ATPase activity]
GO:0030307 [positive regulation of cell growth]
GO:0031011 [Ino80 complex]
GO:0032508 [DNA duplex unwinding]
GO:0034644 [cellular response to UV]
GO:0043014 [alpha-tubulin binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0051225 [spindle assembly]
GO:0051301 [cell division]
GO:0070914 [UV-damage excision repair]
GO:0071479 [cellular response to ionizing radiation]
GO:2000045 [regulation of G1/S transition of mitotic cell cycle]
Show all
 1556 aa
176.8 kDa 		No 0
INO80-201
ENSP00000384686
ENST00000401393
Q9ULG1 [Direct mapping]
DNA helicase INO80
A0A024R9R7 [Target identity:100%; Query identity:100%]
INO80 complex homolog 1 (S. cerevisiae), isoform CRA_b
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000070 [mitotic sister chromatid segregation]
GO:0000724 [double-strand break repair via homologous recombination]
GO:0003677 [DNA binding]
GO:0003678 [DNA helicase activity]
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005874 [microtubule]
GO:0006302 [double-strand break repair]
GO:0006338 [chromatin remodeling]
GO:0010571 [positive regulation of nuclear cell cycle DNA replication]
GO:0016817 [hydrolase activity, acting on acid anhydrides]
GO:0016887 [ATPase activity]
GO:0030307 [positive regulation of cell growth]
GO:0031011 [Ino80 complex]
GO:0032508 [DNA duplex unwinding]
GO:0034644 [cellular response to UV]
GO:0043014 [alpha-tubulin binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0051225 [spindle assembly]
GO:0051301 [cell division]
GO:0070914 [UV-damage excision repair]
GO:0071479 [cellular response to ionizing radiation]
GO:2000045 [regulation of G1/S transition of mitotic cell cycle]
Show all
 1556 aa
176.8 kDa 		No 0
INO80-202
ENSP00000483661
ENST00000616814
A0A087X0U7 [Direct mapping]
DNA helicase INO80
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 192 aa
21.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.