Cell atlas - VPS13C - The Human Protein Atlas

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VPS13C

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Microtubules

Human cell
	Microtubules

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GENERAL INFORMATION
Gene name	VPS13C
Gene description	Vacuolar protein sorting 13 homolog C (S. cerevisiae)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the microtubules.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Microtubules (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA043507
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the microtubules.

Main location

Microtubules (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA043507	HeLa	Microtubules
	HPA043507	RT4	Microtubules
	HPA043507	U-2 OS	Microtubules

GENE INFORMATION
Gene name	VPS13C (HGNC Symbol)
Synonyms	FLJ10381, FLJ20136, KIAA1421
Description	Vacuolar protein sorting 13 homolog C (S. cerevisiae) (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the vacuolar protein sorting-associated 13 gene family. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
Chromosome	15
Cytoband	q22.2
Chromosome location (bp)	61852389 - 62060473
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129003 (version 83.38)
Entrez gene	54832
UniProt	Q709C8 (UniProt - Evidence at protein level)
neXtProt	NX_Q709C8
Antibodypedia	VPS13C antibodies

PROTEIN BROWSER

VPS13C-001	VPS13C-002	VPS13C-003	VPS13C-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
VPS13C-001 ENSP00000249837 ENST00000249837	Q709C8 [Direct mapping] Vacuolar protein sorting-associated protein 13C Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0005623 [cell] GO:0006623 [protein targeting to vacuole] GO:0019898 [extrinsic component of membrane] GO:0045053 [protein retention in Golgi apparatus] GO:0070062 [extracellular exosome] Show all	3710 aa 417.3 kDa	No	0
VPS13C-002 ENSP00000261517 ENST00000261517	Q709C8 [Direct mapping] Vacuolar protein sorting-associated protein 13C Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0005623 [cell] GO:0006623 [protein targeting to vacuole] GO:0019898 [extrinsic component of membrane] GO:0045053 [protein retention in Golgi apparatus] GO:0070062 [extracellular exosome] Show all	3753 aa 422.4 kDa	No	0
VPS13C-003 ENSP00000379233 ENST00000395896	Q709C8 [Direct mapping] Vacuolar protein sorting-associated protein 13C Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0005623 [cell] GO:0006623 [protein targeting to vacuole] GO:0019898 [extrinsic component of membrane] GO:0045053 [protein retention in Golgi apparatus] GO:0070062 [extracellular exosome] Show all	3628 aa 408.2 kDa	No	0
VPS13C-004 ENSP00000379235 ENST00000395898	Q709C8 [Direct mapping] Vacuolar protein sorting-associated protein 13C Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0005623 [cell] GO:0006623 [protein targeting to vacuole] GO:0019898 [extrinsic component of membrane] GO:0045053 [protein retention in Golgi apparatus] GO:0070062 [extracellular exosome] Show all	3585 aa 403.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.